| Literature DB >> 32710311 |
Xue Sun1, Lei Song1, Wenjuan Yang1, Lili Zhang1, Meng Liu1, Xiaoshuang Li1, Geng Tian1, Weiwei Wang2.
Abstract
Nanopore sequencing is a method for determining the order and modifications of DNA/RNA nucleotides by detecting the electric current variations when DNA/RNA oligonucleotides pass through the nanometer-sized hole (nanopore). Nanopore-based DNA analysis techniques have been commercialized by Oxford Nanopore Technologies, NabSys, and Sequenom, and widely used in scientific researches recently including human genomics, cancer, metagenomics, plant sciences, etc., moreover, it also has potential applications in the field of healthcare due to its fast turn-around time, portable and real-time data analysis. Those features make it a promising technology for the point-of-care testing (POCT) and its potential clinical applications are briefly discussed in this chapter.Entities:
Keywords: Integration site; Nanopore sequencing, point-of-care testing; Structure variation; Tumor suppressor gene
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Year: 2020 PMID： 32710311 DOI： 10.1007/978-1-0716-0904-0_2
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745