| Literature DB >> 32706087 |
J Solis-García Del Pozo1, M F Galindo, E Nava, J Jordán.
Abstract
The pandemic caused by the new SARS-CoV2 coronavirus has led to an effort to find treatments that are effective against this disease that the World Health Organization calls COVID-19. In severe cases of COVID-19, there is an increase in cytokines, among which IL-6 seems to play an important role. A search has been performed for studies using IL-6 blocking drugs (tocilizumab, siltuximab, and sarilumab) in PubMed, Web of Science, and Scopus. Also, a search of ongoing trials registered at clinicaltrials.gov was performed. We found very little published clinical experience with these drugs, consisting mainly of case reports or case series with few patients. The results of clinical trials are necessary to clarify the role of these drugs in patients with COVID-19.Entities:
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Year: 2020 PMID： 32706087 DOI： 10.26355/eurrev_202007_21916
Source DB: PubMed Journal: Eur Rev Med Pharmacol Sci ISSN： 1128-3602 Impact factor: 3.507