Jillian C Trabulsi1, Alissa D Smethers2, Jessica R Eosso1, Mia A Papas3, Virginia A Stallings4, Julie A Mennella2. 1. Department of Behavioral Health and Nutrition, University of Delaware, Newark, Delaware, USA. 2. Monell Chemical Senses Center, Philadelphia, Pennsylvania, USA. 3. The Value Institute, Christiana Care Health System, Newark, Delaware, USA. 4. The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Abstract
BACKGROUND: Early rapid weight gain (RWG) increases, whereas longer durations of breastfeeding decreases, odds for later obesity. OBJECTIVES: To determine the independent and interactive effects of early weight gain and diet on infant weight status trajectories and odds for overweight at 1 year. METHODS: We conducted secondary analysis on data from two longitudinal trials with repeated anthropometric measures. One trial consisted of predominantly or exclusively breastfed (BF, n = 97) infants, whereas the other consisted of exclusively formula-fed (FF, n = 113) infants. Weight-for-length z-score (WLZ) change from 0.5 to 4.5 months was used to categorize early weight gain as slow (<-0.67; SWG), normal (-0.67 to 0.67; NWG) or rapid (>0.67; RWG). Linear-mixed effects models were fit to examine the independent effects and interaction of early diet (BF, FF) and weight gain (SWG, NWG, RWG) groups on WLZ trajectories; logistic regression was used to assess odds for overweight at 1 year. RESULTS: While similar percentages (41%) of BF and FF infants experienced RWG, we found a significant diet × early weight gain group interaction (P < .001) on weight status. At 1 year, the WLZ of FF infants with RWG (1.57 ± 0.99) was twice that of BF infants with RWG (0.83 ± 0.92). Using BF infants with NWG as the reference group, FF infants with RWG had increased odds [OR: 25.3 (95% CI: 3.21, 199.7)] for overweight at 1 year, whereas BF infants with RWG did not. CONCLUSIONS: Early diet interacts with early weight gain and influences weight status trajectories and overweight risk at 1 year.
BACKGROUND: Early rapid weight gain (RWG) increases, whereas longer durations of breastfeeding decreases, odds for later obesity. OBJECTIVES: To determine the independent and interactive effects of early weight gain and diet on infant weight status trajectories and odds for overweight at 1 year. METHODS: We conducted secondary analysis on data from two longitudinal trials with repeated anthropometric measures. One trial consisted of predominantly or exclusively breastfed (BF, n = 97) infants, whereas the other consisted of exclusively formula-fed (FF, n = 113) infants. Weight-for-length z-score (WLZ) change from 0.5 to 4.5 months was used to categorize early weight gain as slow (<-0.67; SWG), normal (-0.67 to 0.67; NWG) or rapid (>0.67; RWG). Linear-mixed effects models were fit to examine the independent effects and interaction of early diet (BF, FF) and weight gain (SWG, NWG, RWG) groups on WLZ trajectories; logistic regression was used to assess odds for overweight at 1 year. RESULTS: While similar percentages (41%) of BF and FF infants experienced RWG, we found a significant diet × early weight gain group interaction (P < .001) on weight status. At 1 year, the WLZ of FF infants with RWG (1.57 ± 0.99) was twice that of BF infants with RWG (0.83 ± 0.92). Using BF infants with NWG as the reference group, FF infants with RWG had increased odds [OR: 25.3 (95% CI: 3.21, 199.7)] for overweight at 1 year, whereas BF infants with RWG did not. CONCLUSIONS: Early diet interacts with early weight gain and influences weight status trajectories and overweight risk at 1 year.
Authors: Katherine E Heck; Paula Braveman; Catherine Cubbin; Gilberto F Chávez; John L Kiely Journal: Public Health Rep Date: 2006 Jan-Feb Impact factor: 2.792
Authors: Julie A Mennella; Loma Inamdar; Naomi Pressman; Joan I Schall; Mia A Papas; Dale Schoeller; Virginia A Stallings; Jillian C Trabulsi Journal: Am J Clin Nutr Date: 2018-11-01 Impact factor: 7.045
Authors: Megan E Petrov; Nana Jiao; Sarada S Panchanathan; Elizabeth Reifsnider; Dean V Coonrod; Li Liu; Rosa Krajmalnik-Brown; Haiwei Gu; Laurie A Davidson; Robert S Chapkin; Corrie M Whisner Journal: BMC Pediatr Date: 2021-08-31 Impact factor: 2.567
Authors: Julie A Mennella; Alissa D Smethers; Jessica E Decker; Michelle T Delahanty; Virginia A Stallings; Jillian C Trabulsi Journal: Nutrients Date: 2021-11-04 Impact factor: 5.717