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Literature DB >> 32705590

Impact of Phospholipid Transfer Protein in Lipid Metabolism and Cardiovascular Diseases.

Abstract

PLTP plays an important role in lipoprotein metabolism and cardiovascular disease development in humans; however, the mechanisms are still not completely understood. In mouse models, PLTP deficiency reduces cardiovascular disease, while its overexpression induces it. Therefore, we used mouse models to investigate the involved mechanisms. In this chapter, the recent main progresses in the field of PLTP research are summarized, and our focus is on the relationship between PLTP and lipoprotein metabolism, as well as PLTP and cardiovascular diseases.

Entities: CellLine Chemical Disease Gene Species

Keywords: Cardiovascular diseases; HDL; Lipoprotein; Phospholipid transfer protein; VLDL

Mesh：

Substances：

Year: 2020 PMID： 32705590 PMCID： PMC8025695 DOI： 10.1007/978-981-15-6082-8_1

Source DB: PubMed Journal: Adv Exp Med Biol ISSN： 0065-2598 Impact factor: 2.622

121 in total

1. Widespread distribution of PLTP in human CNS: evidence for PLTP synthesis by glia and neurons, and increased levels in Alzheimer's disease.

Authors: Simona Vuletic; Lee-Way Jin; Santica M Marcovina; Elaine R Peskind; Thomas Moller; John J Albers
Journal: J Lipid Res Date: 2003-04-01 Impact factor: 5.922

2. Anti-inflammatory effects of phospholipid transfer protein (PLTP) deficiency in mice.

Authors: Axel Schlitt; Jin Liu; Daoguang Yan; Mary Mondragon-Escorpizo; Allen J Norin; Xian-Cheng Jiang
Journal: Biochim Biophys Acta Date: 2005-01-19

3. Plasma phospholipid transfer protein deficiency in mice is associated with a reduced thrombotic response to acute intravascular oxidative stress.

Authors: Catherine Desrumaux; Valérie Deckert; Stéphanie Lemaire-Ewing; Claude Mossiat; Anne Athias; David Vandroux; Laure Dumont; Serge Monier; Jean-Paul Pais de Barros; Alexis Klein; Emmanuel De Maistre; Denis Blache; Alain Beley; Christine Marie; Philippe Garnier; Laurent Lagrost
Journal: Arterioscler Thromb Vasc Biol Date: 2010-09-23 Impact factor: 8.311

4. Atheroprotective potential of macrophage-derived phospholipid transfer protein in low-density lipoprotein receptor-deficient mice is overcome by apolipoprotein AI overexpression.

Authors: David T Valenta; Nicolas Ogier; Gary Bradshaw; Audrey S Black; David J Bonnet; Laurent Lagrost; Linda K Curtiss; Catherine M Desrumaux
Journal: Arterioscler Thromb Vasc Biol Date: 2006-05-04 Impact factor: 8.311

5. Early decreases in plasma lipid transfer proteins during weight reduction.

Authors: Themistoklis Tzotzas; Laure Dumont; Athanasios Triantos; Michael Karamouzis; Theodoros Constantinidis; Laurent Lagrost
Journal: Obesity (Silver Spring) Date: 2006-06 Impact factor: 5.002

6. Effects of apolipoprotein M in uremic atherosclerosis.

Authors: Markus Høybye Bosteen; Eva Martha Madsen Svarrer; Line Stattau Bisgaard; Torben Martinussen; Marie Madsen; Lars Bo Nielsen; Christina Christoffersen; Tanja Xenia Pedersen
Journal: Atherosclerosis Date: 2017-08-18 Impact factor: 5.162

7. Phospholipid transfer protein interacts with and stabilizes ATP-binding cassette transporter A1 and enhances cholesterol efflux from cells.

Authors: John F Oram; Gertrud Wolfbauer; Ashley M Vaughan; Chongren Tang; John J Albers
Journal: J Biol Chem Date: 2003-10-14 Impact factor: 5.157

8. Phospholipid transfer protein deficiency ameliorates diet-induced hypercholesterolemia and inflammation in mice.

Authors: Lorraine Shelly; Lori Royer; Thomas Sand; Heather Jensen; Yi Luo
Journal: J Lipid Res Date: 2008-01-14 Impact factor: 5.922

9. PLTP activity is a risk factor for subsequent cardiovascular events in CAD patients under statin therapy: the AtheroGene study.

Authors: Axel Schlitt; Stefan Blankenberg; Christoph Bickel; Karl J Lackner; Gunnar H Heine; Michael Buerke; Karl Werdan; Lars Maegdefessel; Uwe Raaz; Hans J Rupprecht; Thomas Munzel; Xian-Cheng Jiang
Journal: J Lipid Res Date: 2008-11-10 Impact factor: 5.922