Literature DB >> 32704227

Outcomes Comparison of the Veterans' Choice Program With the Veterans Affairs Health Care System for Hepatitis C Treatment.

Daniel Chao1, Hema Buddha1, Chitra Damodaran1, Linda Tran1, Richard Strong1, Christian S Jackson1.   

Abstract

BACKGROUND: The US Department of Veterans Affairs (VA) has been stressed by the large number of veterans requiring direct-acting antiviral (DAA) medications for hepatitis C virus (HCV) treatment. The Veterans Choice Program provides VA patients more options to receive treatment. This study compared the experience of veterans who received HCV treatment through the Veterans Choice Program and those that received treatment at the VA Loma Linda Healthcare System (VALLHCS) in fiscal year (FY) 2016.
METHODS: A chart review was performed on all veterans referred by VALLHCS to Choice for HCV treatment during FY 2016, and matched to veterans who received treatment at VALLHCS. Data collected included Fibrosis-4 score (Fib-4), platelet count, days elapsed between time of referral and time of appointment (wait time), rate of sustained virologic response at 12 weeks (SVR12), reason for treatment failure, and cost effectiveness.
RESULTS: One hundred veterans were referred to Choice; 71 were seen at least once by a Choice provider, and 61 completed a treatment course. Mean Fib-4 and platelet count was 1.9 and 228,000 for the Choice population and 3.4 and 158,000 for the VALLHCS population, respectively. There was no difference in SVR12 rate. Mean wait time was 42 days for Choice vs 29 days for VALLHCS (P < .001). Choice health care providers incurred a mean $8,561.40 in additional costs per veteran seen.
CONCLUSIONS: While treatment success rates were similar between Choice and VALLHCS, the degree of liver fibrosis was more advanced in the VALLHCS population. The wait time for care was longer with Choice compared with a direct referral within the VA. While Choice offers a potential solution to providing care for veterans, the current program has unique problems that must be considered.
Copyright © 2020 Frontline Medical Communications Inc., Parsippany, NJ, USA.

Entities:  

Year:  2020        PMID: 32704227      PMCID: PMC7373074     

Source DB:  PubMed          Journal:  Fed Pract        ISSN: 1078-4497


  10 in total

1.  Elevated prevalence of hepatitis C infection in users of United States veterans medical centers.

Authors:  Jason A Dominitz; Edward J Boyko; Thomas D Koepsell; Patrick J Heagerty; Charles Maynard; Jennifer L Sporleder; Andrew Stenhouse; Mitchel A Kling; William Hrushesky; Charles Zeilman; Stephen Sontag; Nikunj Shah; Fernando Ona; Bhupinder Anand; Marc Subik; Thomas F Imperiale; Samer Nakhle; Sam B Ho; Edmund J Bini; Bruce Lockhart; Jawad Ahmad; Anna Sasaki; Brian van der Linden; Doris Toro; Jaime Martinez-Souss; Vivek Huilgol; Seth Eisen; Keith A Young
Journal:  Hepatology       Date:  2005-01       Impact factor: 17.425

2.  Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV coinfection.

Authors:  Richard K Sterling; Eduardo Lissen; Nathan Clumeck; Ricard Sola; Mendes Cassia Correa; Julio Montaner; Mark S Sulkowski; Francesca J Torriani; Doug T Dieterich; David L Thomas; Diethelm Messinger; Mark Nelson
Journal:  Hepatology       Date:  2006-06       Impact factor: 17.425

Review 3.  Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus.

Authors: 
Journal:  Hepatology       Date:  2015-08-04       Impact factor: 17.425

4.  Distribution of hepatitis C virus genotypes in a diverse US integrated health care population.

Authors:  M Michele Manos; Valentina A Shvachko; Rosemary C Murphy; Jean Marie Arduino; Norah J Shire
Journal:  J Med Virol       Date:  2012-11       Impact factor: 2.327

5.  Epidemiology of hepatitis C virus infection in American veterans.

Authors:  R C Cheung
Journal:  Am J Gastroenterol       Date:  2000-03       Impact factor: 10.864

6.  Barriers to treatment of chronic hepatitis C with direct acting antivirals in an urban clinic.

Authors:  Miguel Malespin; Ciel Harris; Ozdemir Kanar; Kelly Jackman; Carmen Smotherman; Abbey Johnston; Julie Ferm; Silvio W de Melo; James S Scolapio; David R Nelson; Scott J Cotler
Journal:  Ann Hepatol       Date:  2019-04-12       Impact factor: 2.400

7.  Platelet count and sustained virological response in hepatitis C treatment.

Authors:  Tatsuo Kanda; Keizo Kato; Akihito Tsubota; Nobuo Takada; Takayoshi Nishino; Shigeru Mikami; Tatsuo Miyamura; Daisuke Maruoka; Shuang Wu; Shingo Nakamoto; Makoto Arai; Keiichi Fujiwara; Fumio Imazeki; Osamu Yokosuka
Journal:  World J Hepatol       Date:  2013-04-27

8.  Effectiveness of Sofosbuvir, Ledipasvir/Sofosbuvir, or Paritaprevir/Ritonavir/Ombitasvir and Dasabuvir Regimens for Treatment of Patients With Hepatitis C in the Veterans Affairs National Health Care System.

Authors:  George N Ioannou; Lauren A Beste; Michael F Chang; Pamela K Green; Elliott Lowy; Judith I Tsui; Feng Su; Kristin Berry
Journal:  Gastroenterology       Date:  2016-06-04       Impact factor: 22.682

9.  Survival and prognostic factors in 366 patients with compensated cirrhosis type B: a multicenter study. The Investigators of the European Concerted Action on Viral Hepatitis (EUROHEP).

Authors:  G Realdi; G Fattovich; S Hadziyannis; S W Schalm; P Almasio; J Sanchez-Tapias; E Christensen; G Giustina; F Noventa
Journal:  J Hepatol       Date:  1994-10       Impact factor: 25.083

10.  Chronic hepatitis C virus infection in the United States, National Health and Nutrition Examination Survey 2003 to 2010.

Authors:  Maxine M Denniston; Ruth B Jiles; Jan Drobeniuc; R Monina Klevens; John W Ward; Geraldine M McQuillan; Scott D Holmberg
Journal:  Ann Intern Med       Date:  2014-03-04       Impact factor: 25.391

  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.