Literature DB >> 32701395

Designing Pull Funding For A COVID-19 Vaccine.

Christopher M Snyder1, Kendall Hoyt2, Dimitrios Gouglas3, Thomas Johnston4, James Robinson5.   

Abstract

A widely accessible vaccine is essential to mitigate the health and economic ravages of coronavirus disease 2019 (COVID-19). Without appropriate incentives and coordination, however, firms might not respond at sufficient speed or scale, and competition among countries for limited supply could drive up prices and undercut efficient allocation. Programs relying on "push" incentives (direct cost reimbursement) can be complicated by the funder's inability to observe firms' private cost information. To address these challenges, we propose a "pull" program that incentivizes late-stage development (Phase III trials and manufacturing) for COVID-19 vaccines by awarding advance purchase agreements to bidding firms. Using novel cost and demand data, we calculated the optimal size and number of awards. In baseline simulations, the optimal program induced the participation of virtually all ten viable vaccine candidates, spending an average of $110 billion to generate net benefits of $2.8 trillion-nearly double the net benefits generated by the free market.

Entities:  

Keywords:  Advance market commitment; COVID-19; Costs and spending; Health policy; Incentives; Manufacturing; Markets; Pandemics; Pharmaceutical innovation; Pharmaceuticals; Prescription drug costs; Research and development; coronavirus; vaccines

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Substances:

Year:  2020        PMID: 32701395     DOI: 10.1377/hlthaff.2020.00646

Source DB:  PubMed          Journal:  Health Aff (Millwood)        ISSN: 0278-2715            Impact factor:   6.301


  2 in total

1.  How Should the World Pay for a Coronavirus Disease (COVID-19) Vaccine?

Authors:  Adrian Towse; Kalipso Chalkidou; Isobel Firth; Hannah Kettler; Rachel Silverman
Journal:  Value Health       Date:  2021-02-19       Impact factor: 5.725

2.  Adaptive R&D contract for urgently needed drugs: Lessons from COVID-19 vaccine development.

Authors:  Ji-Hung Ryan Choi; Jiho Yoon; Ju Myung Song
Journal:  Omega       Date:  2022-08-09       Impact factor: 8.673

  2 in total

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