Karl A Miller1,2,3, Marcus Radauer4, J N Buchwald5, T W McGlennon6, Elisabeth Ardelt-Gattinger7. 1. Diakonissen Wehrle Private Hospital, Salzburg, Austria. karl@miller.co.at. 2. Hospital Hallein, Salzburg, Austria. karl@miller.co.at. 3. Bariatric and Metabolic Unit, Diakonissen & Wehrle Private Clinic, Guggenbichlerstrasse 20, A-5026, Salzburg, Austria. karl@miller.co.at. 4. Hospital Hallein, Salzburg, Austria. 5. Division of Scientific Research Writing, Medwrite Medical Communications, Maiden Rock, WI, USA. 6. McGlennon MotiMetrics (M3), Maiden Rock, WI, USA. 7. University of Salzburg, Salzburg, Austria.
Abstract
BACKGROUND: The novel banded one-anastomosis gastric bypass (B-OAGB) procedure has not previously been reported in super-obese patients over the long term. In this pilot study, outcomes in patients with a mean baseline body mass index (BMI, kg/m2) of ≥ 50 who underwent B-OAGB were evaluated through 5-year follow-up. PATIENTS AND METHODS: Total weight loss (TWL), excess weight loss (EWL), BMI evolution, and changes in type 2 diabetes biomarkers were analyzed prospectively in super-obese patients who underwent B-OAGB. Paired samples t tests were used to assess weight outcome change from baseline through 5-year follow-up and 95% CIs were calculated. The Bariatric Outcomes and Reporting System (BAROS) was used to assess surgical success at 3 time points. RESULTS: Between October 2013 and February 2014, a 12-patient pilot cohort (mean baseline BMI 57.5 ± 6.3) underwent B-OAGB. No perioperative complications were observed within 30 days. Five-year mean BMI was 31.2 ± 5.4, a BMI loss of 25.9 (TWL 45.3 ± 7.5%; EWL 72.2 ± 12.8%). Between 11 and 24 months following surgery, 3 patients required band removal; each had one complication (1 stasis esophagitis and recurrent vomiting; 1 hypoalbuminemia; 1 anemia). There was no mortality. Long-term B-OAGB BAROS subscale and composite scores were comparable to other major bariatric procedures. CONCLUSIONS: In a pilot study of super-obese patients who underwent B-OAGB, excellent durable BMI loss of 25.9 kg/m2 (EWL 72.2%) at 5 years was achieved with an acceptable level of reoperation. More B-OAGB long-term follow-up studies are necessary to provide definitive conclusions regarding this combination bariatric procedure.
BACKGROUND: The novel banded one-anastomosis gastric bypass (B-OAGB) procedure has not previously been reported in super-obesepatients over the long term. In this pilot study, outcomes in patients with a mean baseline body mass index (BMI, kg/m2) of ≥ 50 who underwent B-OAGB were evaluated through 5-year follow-up. PATIENTS AND METHODS: Total weight loss (TWL), excess weight loss (EWL), BMI evolution, and changes in type 2 diabetes biomarkers were analyzed prospectively in super-obesepatients who underwent B-OAGB. Paired samples t tests were used to assess weight outcome change from baseline through 5-year follow-up and 95% CIs were calculated. The Bariatric Outcomes and Reporting System (BAROS) was used to assess surgical success at 3 time points. RESULTS: Between October 2013 and February 2014, a 12-patient pilot cohort (mean baseline BMI 57.5 ± 6.3) underwent B-OAGB. No perioperative complications were observed within 30 days. Five-year mean BMI was 31.2 ± 5.4, a BMI loss of 25.9 (TWL 45.3 ± 7.5%; EWL 72.2 ± 12.8%). Between 11 and 24 months following surgery, 3 patients required band removal; each had one complication (1 stasis esophagitis and recurrent vomiting; 1 hypoalbuminemia; 1 anemia). There was no mortality. Long-term B-OAGB BAROS subscale and composite scores were comparable to other major bariatric procedures. CONCLUSIONS: In a pilot study of super-obesepatients who underwent B-OAGB, excellent durable BMI loss of 25.9 kg/m2 (EWL 72.2%) at 5 years was achieved with an acceptable level of reoperation. More B-OAGB long-term follow-up studies are necessary to provide definitive conclusions regarding this combination bariatric procedure.
Authors: Cari M Kitahara; Alan J Flint; Amy Berrington de Gonzalez; Leslie Bernstein; Michelle Brotzman; Robert J MacInnis; Steven C Moore; Kim Robien; Philip S Rosenberg; Pramil N Singh; Elisabete Weiderpass; Hans Olov Adami; Hoda Anton-Culver; Rachel Ballard-Barbash; Julie E Buring; D Michal Freedman; Gary E Fraser; Laura E Beane Freeman; Susan M Gapstur; John Michael Gaziano; Graham G Giles; Niclas Håkansson; Jane A Hoppin; Frank B Hu; Karen Koenig; Martha S Linet; Yikyung Park; Alpa V Patel; Mark P Purdue; Catherine Schairer; Howard D Sesso; Kala Visvanathan; Emily White; Alicja Wolk; Anne Zeleniuch-Jacquotte; Patricia Hartge Journal: PLoS Med Date: 2014-07-08 Impact factor: 11.069
Authors: Marta Borges-Canha; João Sérgio Neves; Fernando Mendonça; Maria Manuel Silva; Cláudia Costa; Pedro M Cabral; Vanessa Guerreiro; Rita Lourenço; Patrícia Meira; Daniela Salazar; Maria João Ferreira; Jorge Pedro; Ebrahim Barkoudah; Ana Sande; Eva Lau; Selma B Souto; John Preto; Paula Freitas; Davide Carvalho Journal: Front Endocrinol (Lausanne) Date: 2021-08-12 Impact factor: 5.555