Literature DB >> 32694828

Metabolic reprogramming in polycystic kidney disease explained by super-enhancers and CDK7: new therapeutic targets?

Laura Cassina1, Alessandra Boletta2.   

Abstract

Entities:  

Year:  2020        PMID： 32694828     DOI： 10.1038/s42255-020-0232-7

Source DB:  PubMed          Journal:  Nat Metab        ISSN： 2522-5812


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  1 in total

1.  Super-enhancer-driven metabolic reprogramming promotes cystogenesis in autosomal dominant polycystic kidney disease.

Authors:  Zeyun Mi; Yandong Song; Xinyi Cao; Yi Lu; Zhiheng Liu; Xu Zhu; Meijuan Geng; Yongzhan Sun; Bingxue Lan; Chaoran He; Hui Xiong; Lirong Zhang; Yupeng Chen
Journal:  Nat Metab       Date:  2020-07-13
  1 in total
  1 in total

1.  Intact mitochondrial substrate efflux is essential for prevention of tubular injury in a sex-dependent manner.

Authors:  Allison McCrimmon; Kerin M Cahill; Claudia Kruger; Margaret E Mangelli; Emily Bouffard; Timothy Dobroski; Kelly N Michanczyk; Susan J Burke; Robert C Noland; Daria V Ilatovskaya; Krisztian Stadler
Journal:  JCI Insight       Date:  2022-04-08
  1 in total

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