Daniele De Luca1,2, Pierre Tissieres3, Martin C J Kneyber4, Marc Humbert5,6, Olaf Mercier5,7. 1. Division of Pediatrics and Neonatal Critical Care, "A.Béclère" Medical Centre, Paris Saclay University Hospitals, APHP, Paris, France. dm.deluca@icloud.com. 2. Physiopathology and Therapeutic Innovation Unit-INSERM U999, Paris-Saclay University, Paris, France. dm.deluca@icloud.com. 3. Division of Pediatric Critical Care, Kremlin-Bicetre Medical Centre, Paris Saclay University Hospitals, APHP, Paris, France. 4. Division of Paediatric Intensive Care, Department of Paediatrics, Beatrix Children's Hospital, University Medical Center Groningen, The University of Groningen, Groningen, The Netherlands. 5. Physiopathology and Therapeutic Innovation Unit-INSERM U999, Paris-Saclay University, Paris, France. 6. Division of Pneumology, Kremlin-Bicetre Medical Centre, Paris Saclay University Hospitals, APHP, Paris, France. 7. Department of Thoracic and Vascular Surgery and Heart and Lung Transplantation, Marie Lannelongue Hospital, Paris, France.
Abstract
Lung and heart & lung transplantations in neonates and infants are extreme treatments offered for some life-threatening conditions especially in some North-American centers with promising results. These transplantations are rarely performed in Europe, and we set up a continent-based survey to describe the attitude of European neonatologists and pediatric intensivists on the subject and identify the main indications for this transplantation and the obstacles for the realization of a European lung transplantation program. Conclusion: The main indications for lung transplantation program for neonates and infants are represented by congenital disorders, and physicians indicate as main obstacles the donors' availability. European neonatologists and pediatric intensivists are interested to create a European network to overcome this problem and realize a lung transplantation program for neonates and infants. What is Known: • Lung transplantation in neonates and infants seems to slowly increase, and some North-American centers accumulated a relevant experience. What is New: • European neonatologists and pediatric intensivists are interested in creating a European network for a lung transplantation program for neonates and infants. • The main indications for lung transplantation program for neonates and infants are represented by congenital disorders and main obstacle to lung transplantation is the donors' availability.
Lung and heart & lung transplantations in neonates and infants are extreme treatments offered for some life-threatening conditions especially in some North-American centers with promising results. These transplantations are rarely performed in Europe, and we set up a continent-based survey to describe the attitude of European neonatologists and pediatric intensivists on the subject and identify the main indications for this transplantation and the obstacles for the realization of a European lung transplantation program. Conclusion: The main indications for lung transplantation program for neonates and infants are represented by congenital disorders, and physicians indicate as main obstacles the donors' availability. European neonatologists and pediatric intensivists are interested to create a European network to overcome this problem and realize a lung transplantation program for neonates and infants. What is Known: • Lung transplantation in neonates and infants seems to slowly increase, and some North-American centers accumulated a relevant experience. What is New: • European neonatologists and pediatric intensivists are interested in creating a European network for a lung transplantation program for neonates and infants. • The main indications for lung transplantation program for neonates and infants are represented by congenital disorders and main obstacle to lung transplantation is the donors' availability.
Authors: Alicija Vileito; Christian V Hulzebos; Mona C Toet; Dyvonne H Baptist; Eduard A A Verhagen; Marion J Siebelink Journal: Eur J Pediatr Date: 2021-06-09 Impact factor: 3.183