Aluminium encephalopathy: clinical and immunological features.

Aluminium encephalopathy is a specific syndrome occurring in dialysis patients and linked to high aluminium levels in dialysis water. We present the features of 38 cases seen in a single dialysis and transplantation unit. Serum immunoglobulin levels and the prevalence of histocompatibility antigens are discussed. The syndrome in its complete form is specific and easily recognizable. Careful attention to premonitory symptoms may lead to earlier diagnosis.