| Literature DB >> 32686069 |
Yuki Shinya1, Hirotaka Hasegawa2,3, Mariko Kawashima2, Masahiro Shin2, Wataru Takahashi4, Hiroshi Kobayashi5, Nobuhito Saito2.
Abstract
Alveolar soft part sarcoma (ASPS) is a rare malignancy that typically arises in the trunk or extremities and preferentially metastasises to the brain. Radical resection is generally recommended for cranial metastatic ASPS, but stereotactic radiosurgery (SRS) is a recognised alternative for tumours in surgically challenging locations. Here, we present the case of a 22-year-old female, who underwent SRS and systemic therapy with pazopanib for a metastatic ASPS in the left temporal bone. The tumour was successfully controlled without further intervention over 23 months following SRS, which should be considered for metastatic ASPS when surgical resection is not appropriate.Entities:
Keywords: Alveolar soft part sarcoma; Case report; Hypofractionated radiotherapy; Skull base metastasis; Stereotactic radiosurgery
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Year: 2020 PMID: 32686069 DOI: 10.1007/s00701-020-04496-2
Source DB: PubMed Journal: Acta Neurochir (Wien) ISSN: 0001-6268 Impact factor: 2.216