Scalp and intracerebral P300 in surgery for temporal lobe epilepsy.

We have studied the scalp and intracerebral recordings of 12 patients with intractable temporal lobe epilepsy. The intracerebral P300 provides useful diagnostic information regarding the epileptogenicity of a temporal lobe. The scalp P300, by nature of its bilateral scalp distribution, is unable to be used diagnostically in assessing candidates for possible anterior temporal lobectomy.