Literature DB >> 32681369

Recurring pediatric anaplastic ependymoma with rare peritoneal carcinomatosis: a case report and hypothesis of mechanism.

Ruby G Siada1, Victor M Lu2,3, Jonathan Schwartz1, David J Daniels4,5.   

Abstract

BACKGROUND: Although recurrent anaplastic ependymoma in pediatric patients is not uncommon, recurrent disease leading to widespread metastases to the peritoneum is extremely rare. CASE REPORT: We present a case of an 18-month old male who initially presented with posterior fossa anaplastic ependymoma, who then proceeded to present 1 year later with spinal recurrence, and then 2 years after that with widespread disease involving the intracranial ventricular system and peritoneum.
CONCLUSION: We posit that surgical interventions to treat primary and recurrent presentations in combination with a conduit to the peritoneum via a ventriculoperitoneal shunt contributed to the mechanisms of this complex case.

Entities:  

Keywords:  Anaplastic ependymoma; Dissemination; Metastases; Pediatric; Peritoneal; Shunt

Mesh:

Year:  2020        PMID: 32681369     DOI: 10.1007/s00381-020-04814-0

Source DB:  PubMed          Journal:  Childs Nerv Syst        ISSN: 0256-7040            Impact factor:   1.475


  6 in total

1.  Cerebrospinal fluid cytology in patients with cancer: minimizing false-negative results.

Authors:  M J Glantz; B F Cole; L K Glantz; J Cobb; P Mills; A Lekos; B C Walters; L D Recht
Journal:  Cancer       Date:  1998-02-15       Impact factor: 6.860

2.  Extraneural metastasis of an ependymoma: a rare occurrence.

Authors:  Ahmed Alzahrani; Ali Alassiri; Amna Kashgari; Jihad Alrehaili; Hesham Alshaalan; Reem Zakzouk
Journal:  Neuroradiol J       Date:  2014-04-18

3.  Intracranial ependymoma: long-term results of a policy of surgery and radiotherapy.

Authors:  L J Vanuytsel; E M Bessell; S E Ashley; H J Bloom; M Brada
Journal:  Int J Radiat Oncol Biol Phys       Date:  1992       Impact factor: 7.038

4.  Extraneural metastases in anaplastic ependymoma.

Authors:  Pavan Kumar; Neeraj Rastogi; Manoj Jain; Poonam Chhabra
Journal:  J Cancer Res Ther       Date:  2007 Apr-Jun       Impact factor: 1.805

Review 5.  Extracranial, peritoneal seeding of primary malignant brain tumors through ventriculo-peritoneal shunts in children: Case report and review of the literature.

Authors:  Anand Narayan; George Jallo; Thierry A G M Huisman
Journal:  Neuroradiol J       Date:  2015-10-06

6.  The prognostic value of histological grading of posterior fossa ependymomas in children: a Children's Oncology Group study and a review of prognostic factors.

Authors:  Tarik Tihan; Tianni Zhou; Emi Holmes; Peter C Burger; Sema Ozuysal; Elisabeth J Rushing
Journal:  Mod Pathol       Date:  2007-12-14       Impact factor: 7.842

  6 in total

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