Literature DB >> 32678903

LSD1 inhibition in pHGG: the key to unleashing immunotherapy?

Theodore P Nicolaides1, Rintaro Hashizume2.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2020        PMID： 32678903      PMCID： PMC7523443          DOI： 10.1093/neuonc/noaa171

Source DB:  PubMed          Journal:  Neuro Oncol        ISSN： 1522-8517            Impact factor:   12.300


× No keyword cloud information.
  10 in total

1.  Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma.

Authors:  Jeremy Schwartzentruber; Andrey Korshunov; Xiao-Yang Liu; David T W Jones; Elke Pfaff; Karine Jacob; Dominik Sturm; Adam M Fontebasso; Dong-Anh Khuong Quang; Martje Tönjes; Volker Hovestadt; Steffen Albrecht; Marcel Kool; Andre Nantel; Carolin Konermann; Anders Lindroth; Natalie Jäger; Tobias Rausch; Marina Ryzhova; Jan O Korbel; Thomas Hielscher; Peter Hauser; Miklos Garami; Almos Klekner; Laszlo Bognar; Martin Ebinger; Martin U Schuhmann; Wolfram Scheurlen; Arnulf Pekrun; Michael C Frühwald; Wolfgang Roggendorf; Christoph Kramm; Matthias Dürken; Jeffrey Atkinson; Pierre Lepage; Alexandre Montpetit; Magdalena Zakrzewska; Krzystof Zakrzewski; Pawel P Liberski; Zhifeng Dong; Peter Siegel; Andreas E Kulozik; Marc Zapatka; Abhijit Guha; David Malkin; Jörg Felsberg; Guido Reifenberger; Andreas von Deimling; Koichi Ichimura; V Peter Collins; Hendrik Witt; Till Milde; Olaf Witt; Cindy Zhang; Pedro Castelo-Branco; Peter Lichter; Damien Faury; Uri Tabori; Christoph Plass; Jacek Majewski; Stefan M Pfister; Nada Jabado
Journal:  Nature       Date:  2012-01-29       Impact factor: 49.962

2.  Pharmacologic inhibition of lysine-specific demethylase 1 as a therapeutic and immune-sensitization strategy in pediatric high-grade glioma.

Authors:  Cavan P Bailey; Mary Figueroa; Achintyan Gangadharan; Yanwen Yang; Megan M Romero; Bridget A Kennis; Sridevi Yadavilli; Verlene Henry; Tiara Collier; Michelle Monje; Dean A Lee; Linghua Wang; Javad Nazarian; Vidya Gopalakrishnan; Wafik Zaky; Oren J Becher; Joya Chandra
Journal:  Neuro Oncol       Date:  2020-09-29       Impact factor: 12.300

3.  Preclinical activity of combined HDAC and KDM1A inhibition in glioblastoma.

Authors:  Melissa M Singh; Blake Johnson; Avinashnarayan Venkatarayan; Elsa R Flores; Jianping Zhang; Xiaoping Su; Michelle Barton; Frederick Lang; Joya Chandra
Journal:  Neuro Oncol       Date:  2015-03-19       Impact factor: 12.300

Review 4.  Reversible inhibitors of LSD1 as therapeutic agents in acute myeloid leukemia: clinical significance and progress to date.

Authors:  Daniel P Mould; Alison E McGonagle; Daniel H Wiseman; Emma L Williams; Allan M Jordan
Journal:  Med Res Rev       Date:  2014-11-24       Impact factor: 12.944

5.  Immune Checkpoint Inhibition for Hypermutant Glioblastoma Multiforme Resulting From Germline Biallelic Mismatch Repair Deficiency.

Authors:  Eric Bouffet; Valérie Larouche; Brittany B Campbell; Daniele Merico; Richard de Borja; Melyssa Aronson; Carol Durno; Joerg Krueger; Vanja Cabric; Vijay Ramaswamy; Nataliya Zhukova; Gary Mason; Roula Farah; Samina Afzal; Michal Yalon; Gideon Rechavi; Vanan Magimairajan; Michael F Walsh; Shlomi Constantini; Rina Dvir; Ronit Elhasid; Alyssa Reddy; Michael Osborn; Michael Sullivan; Jordan Hansford; Andrew Dodgshun; Nancy Klauber-Demore; Lindsay Peterson; Sunil Patel; Scott Lindhorst; Jeffrey Atkinson; Zane Cohen; Rachel Laframboise; Peter Dirks; Michael Taylor; David Malkin; Steffen Albrecht; Roy W R Dudley; Nada Jabado; Cynthia E Hawkins; Adam Shlien; Uri Tabori
Journal:  J Clin Oncol       Date:  2016-03-21       Impact factor: 44.544

Review 6.  Influence of metabolism on epigenetics and disease.

Authors:  William G Kaelin; Steven L McKnight
Journal:  Cell       Date:  2013-03-28       Impact factor: 41.582

7.  Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma.

Authors:  Rintaro Hashizume; Noemi Andor; Yuichiro Ihara; Robin Lerner; Haiyun Gan; Xiaoyue Chen; Dong Fang; Xi Huang; Maxwell W Tom; Vy Ngo; David Solomon; Sabine Mueller; Pamela L Paris; Zhiguo Zhang; Claudia Petritsch; Nalin Gupta; Todd A Waldman; C David James
Journal:  Nat Med       Date:  2014-11-17       Impact factor: 53.440

Review 8.  Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targeting.

Authors:  Emily R Theisen; Kathleen I Pishas; Ranajeet S Saund; Stephen L Lessnick
Journal:  Oncotarget       Date:  2016-04-05

9.  Molecular, Pathological, Radiological, and Immune Profiling of Non-brainstem Pediatric High-Grade Glioma from the HERBY Phase II Randomized Trial.

Authors:  Alan Mackay; Anna Burford; Valeria Molinari; David T W Jones; Elisa Izquierdo; Jurriaan Brouwer-Visser; Felice Giangaspero; Christine Haberler; Torsten Pietsch; Thomas S Jacques; Dominique Figarella-Branger; Daniel Rodriguez; Paul S Morgan; Pichai Raman; Angela J Waanders; Adam C Resnick; Maura Massimino; Maria Luisa Garrè; Helen Smith; David Capper; Stefan M Pfister; Thomas Würdinger; Rachel Tam; Josep Garcia; Meghna Das Thakur; Gilles Vassal; Jacques Grill; Tim Jaspan; Pascale Varlet; Chris Jones
Journal:  Cancer Cell       Date:  2018-05-14       Impact factor: 31.743

10.  Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma.

Authors:  Alan Mackay; Anna Burford; Diana Carvalho; Elisa Izquierdo; Janat Fazal-Salom; Kathryn R Taylor; Lynn Bjerke; Matthew Clarke; Mara Vinci; Meera Nandhabalan; Sara Temelso; Sergey Popov; Valeria Molinari; Pichai Raman; Angela J Waanders; Harry J Han; Saumya Gupta; Lynley Marshall; Stergios Zacharoulis; Sucheta Vaidya; Henry C Mandeville; Leslie R Bridges; Andrew J Martin; Safa Al-Sarraj; Christopher Chandler; Ho-Keung Ng; Xingang Li; Kun Mu; Saoussen Trabelsi; Dorra H'mida-Ben Brahim; Alexei N Kisljakov; Dmitry M Konovalov; Andrew S Moore; Angel Montero Carcaboso; Mariona Sunol; Carmen de Torres; Ofelia Cruz; Jaume Mora; Ludmila I Shats; João N Stavale; Lucas T Bidinotto; Rui M Reis; Natacha Entz-Werle; Michael Farrell; Jane Cryan; Darach Crimmins; John Caird; Jane Pears; Michelle Monje; Marie-Anne Debily; David Castel; Jacques Grill; Cynthia Hawkins; Hamid Nikbakht; Nada Jabado; Suzanne J Baker; Stefan M Pfister; David T W Jones; Maryam Fouladi; André O von Bueren; Michael Baudis; Adam Resnick; Chris Jones
Journal:  Cancer Cell       Date:  2017-09-28       Impact factor: 31.743
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.