Literature DB >> 32672484

Molecular genetic changes in solid pseudopapillary neoplasms (SPN) of the pancreas.

Elisa Rodriguez-Matta1, Amanda Hemmerich2, Jason Starr3, Kabir Mody3, Eric A Severson2, Gerardo Colon-Otero3.   

Abstract

Entities:  

Keywords:  Solid pseudopapillary neoplasms of the pancreas are commonly associated with pathogenic point mutations in the CTNNB1 gene. Our series identified CTNNB1 mutations in 93% of the cases; each in 29% of the cases; most commonly in positions 32 and 37. Additional pathogenic mutations in other cancer associated genes are common; present in 64% of our cases. Comprehensive genomic profiling identified potentially actionable genomic alterations and mutations in DNA repair genes

Year:  2020        PMID： 32672484      PMCID： PMC8081262          DOI： 10.1080/0284186X.2020.1792549

Source DB:  PubMed          Journal:  Acta Oncol        ISSN： 0284-186X            Impact factor:   4.089


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  28 in total

1.  Comparison of the clinicopathological features of pancreatic solid pseudopapillary neoplasms between males and females: gender does matter.

Authors:  Yi Zou; Yan Huang; Bo Hong; Xueping Xiang; Bin Zhou; Shumei Wei
Journal:  Histol Histopathol       Date:  2019-09-03       Impact factor: 2.303

2.  Pathological differential diagnosis of solid-pseudopapillary neoplasm and endocrine tumors of the pancreas.

Authors:  Bao-An Liu; Zhuo-Ming Li; Zhan-San Su; Xiao-Ling She
Journal:  World J Gastroenterol       Date:  2010-02-28       Impact factor: 5.742

3.  Characterization of gene expression and activated signaling pathways in solid-pseudopapillary neoplasm of pancreas.

Authors:  Minhee Park; Minhyung Kim; Daehee Hwang; Misun Park; Won Kyu Kim; Sang Kyum Kim; Jihye Shin; Eun Sung Park; Chang Moo Kang; Young-Ki Paik; Hoguen Kim
Journal:  Mod Pathol       Date:  2013-09-27       Impact factor: 7.842

4.  Constitutively active ESR1 mutations in gynecologic malignancies and clinical response to estrogen-receptor directed therapies.

Authors:  Stéphanie L Gaillard; Kaitlyn J Andreano; Laurie M Gay; Meghan Steiner; Matthew S Jorgensen; Brittany Anne Davidson; Laura J Havrilesky; Angeles Alvarez Secord; Fidel A Valea; Gerardo Colon-Otero; Deborah A Zajchowski; Ching-Yi Chang; Donald P McDonnell; Andrew Berchuck; Julia A Elvin
Journal:  Gynecol Oncol       Date:  2019-04-13       Impact factor: 5.482

5.  Mutation of beta-catenin and its protein accumulation in solid and cystic tumor of the pancreas associated with metastasis.

Authors:  Jiangyong Miao; Takeshi Kusafuka; Seika Kuroda; Akihiro Yoneda; Zhiwei Zhou; Akira Okada
Journal:  Int J Mol Med       Date:  2003-04       Impact factor: 4.101

6.  Solid-pseudopapillary neoplasms of the pancreas in men and women: do they differ?

Authors:  Yu Takahashi; Nobuyoshi Hiraoka; Kaoru Onozato; Tatsuhiro Shibata; Tomoo Kosuge; Yuji Nimura; Yae Kanai; Setsuo Hirohashi
Journal:  Virchows Arch       Date:  2006-03-08       Impact factor: 4.064

7.  CTNNB1 mutational analysis of solid-pseudopapillary neoplasms of the pancreas using endoscopic ultrasound-guided fine-needle aspiration and next-generation deep sequencing.

Authors:  Yoshimasa Kubota; Hiroshi Kawakami; Mitsuteru Natsuizaka; Kazumichi Kawakubo; Katsuji Marukawa; Taiki Kudo; Yoko Abe; Kimitoshi Kubo; Masaki Kuwatani; Yutaka Hatanaka; Tomoko Mitsuhashi; Yoshihiro Matsuno; Naoya Sakamoto
Journal:  J Gastroenterol       Date:  2014-04-04       Impact factor: 7.527

8.  Trends in pancreatic adenocarcinoma incidence and mortality in the United States in the last four decades; a SEER-based study.

Authors:  Anas M Saad; Tarek Turk; Muneer J Al-Husseini; Omar Abdel-Rahman
Journal:  BMC Cancer       Date:  2018-06-25       Impact factor: 4.430

9.  Solid pseudopapillary neoplasms of the pancreas are dependent on the Wnt pathway.

Authors:  Pier Selenica; Nitya Raj; Rahul Kumar; David N Brown; Oriol Arqués; Diane Reidy; David Klimstra; Matija Snuderl; Jonathan Serrano; Héctor G Palmer; Britta Weigelt; Jorge S Reis-Filho; Maurizio Scaltriti
Journal:  Mol Oncol       Date:  2019-07-03       Impact factor: 6.603

10.  Molecular alterations associated with metastases of solid pseudopapillary neoplasms of the pancreas.

Authors:  Eliana Amato; Andrea Mafficini; Kenichi Hirabayashi; Rita T Lawlor; Matteo Fassan; Caterina Vicentini; Stefano Barbi; Pietro Delfino; Katarzyna Sikora; Borislav Rusev; Michele Simbolo; Irene Esposito; Davide Antonello; Antonio Pea; Elisabetta Sereni; Maria Ballotta; Laura Maggino; Giovanni Marchegiani; Nobuyuki Ohike; Laura D Wood; Roberto Salvia; Günter Klöppel; Giuseppe Zamboni; Aldo Scarpa; Vincenzo Corbo
Journal:  J Pathol       Date:  2018-11-27       Impact factor: 7.996
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