Literature DB >> 3267105

Is lactose malabsorption a risk factor in fractures of the elderly?

M Härmä1, E Alhava.   

Abstract

The prevalence of lactose malabsorption (LM) was determined by lactose tolerance tests in 18 women with spinal fragility fractures and 28 women with hip fractures and compared with 35 female controls of the same ethnic background. The association of LM with bone density in the spine, bone mineral density in the distal radius and histomorphometric values of iliac crest biopsies was also evaluated. The prevalence of LM did not differ between the fracture groups and the control subjects. Patients with LM did not differ from those with normal lactose tolerance with regard to bone densitometry or histomorphometric findings in iliac crest biopsies. These results suggest that in Finland LM is not a risk factor for osteopenic fractures in the elderly.

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Year:  1988        PMID: 3267105

Source DB:  PubMed          Journal:  Ann Chir Gynaecol        ISSN: 0355-9521


  3 in total

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Authors:  Nicholas J Timpson; Paul Brennan; Valérie Gaborieau; Lee Moore; David Zaridze; Vsevolod Matveev; Neonilia Szeszenia-Dabrowska; Jolanta Lissowska; Dana Mates; Vladimir Bencko; Lenka Foretova; Vladimir Janout; Wong-Ho Chow; Nathaniel Rothman; Paolo Boffetta; Roger M Harbord; George Davey Smith
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2010-05       Impact factor: 4.254

2.  Calcium supply, bone mineral density and genetically defined lactose maldigestion in a cohort of elderly men.

Authors:  M Gugatschka; A Hoeller; A Fahrleitner-Pammer; H Dobnig; P Pietschmann; S Kudlacek; B Obermayer-Pietsch
Journal:  J Endocrinol Invest       Date:  2007-01       Impact factor: 4.256

3.  Lactase persistence-related genetic variant: population substructure and health outcomes.

Authors:  George Davey Smith; Debbie A Lawlor; Nic J Timpson; Jamil Baban; Matt Kiessling; Ian N M Day; Shah Ebrahim
Journal:  Eur J Hum Genet       Date:  2008-09-17       Impact factor: 4.246

  3 in total

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