Literature DB >> 32669425

Ethical challenges for pediatric liver organoid transplantation.

Sarah A Schneemann1,2, Sarah N Boers1, Johannes J M van Delden1, Edward E S Nieuwenhuis2,3, Sabine A Fuchs4, Annelien L Bredenoord5.   

Abstract

Liver organoid transplantation may be a less invasive alternative to liver transplant, but is it ethically acceptable to include children with liver disease in a first-in-human clinical trial of this new intervention?
Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

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Year:  2020        PMID： 32669425     DOI： 10.1126/scitranslmed.aau8471

Source DB:  PubMed          Journal:  Sci Transl Med        ISSN： 1946-6234            Impact factor:   17.956


  6 in total

1.  Spectroscopic label-free microscopy of changes in live cell chromatin and biochemical composition in transplantable organoids.

Authors:  Giuseppe Pettinato; Mark F Coughlan; Xuejun Zhang; Liming Chen; Umar Khan; Maria Glyavina; Conor J Sheil; Paul K Upputuri; Yuri N Zakharov; Edward Vitkin; Antonino B D'Assoro; Robert A Fisher; Irving Itzkan; Lei Zhang; Le Qiu; Lev T Perelman
Journal:  Sci Adv       Date:  2021-08-18       Impact factor: 14.136

2.  Ethical Challenges in Organoid Use.

Authors:  Vasiliki Mollaki
Journal:  BioTech (Basel)       Date:  2021-06-28

3.  Creation and use of organoids in biomedical research and healthcare: the bioethical and metabioethical issues.

Authors:  Henri-Corto Stoeklé; Achille Ivasilevitch; Geneviève Marignac; Christian Hervé
Journal:  Cell Adh Migr       Date:  2021-12       Impact factor: 3.405

Review 4.  Organoids: a systematic review of ethical issues.

Authors:  Dide de Jongh; Emma K Massey; Eline M Bunnik
Journal:  Stem Cell Res Ther       Date:  2022-07-23       Impact factor: 8.079

Review 5.  Applications of human organoids in the personalized treatment for digestive diseases.

Authors:  Qinying Wang; Fanying Guo; Yutao Jin; Yanlei Ma
Journal:  Signal Transduct Target Ther       Date:  2022-09-27

6.  Patients' perspectives on the derivation and use of organoids.

Authors:  Juli Bollinger; Elizabeth May; Debra Mathews; Mark Donowitz; Jeremy Sugarman
Journal:  Stem Cell Reports       Date:  2021-07-29       Impact factor: 7.765
  6 in total

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