Literature DB >> 32666730

[Treatment of diabetic foot with vaccum sealing drainage combined with transverse tibial bone transport].

Shunan Dong1, Dong Huang2, Lilin Zhu2, Xiaoyan Liu3.   

Abstract

OBJECTIVE: To summarize the effectiveness and experience of Wanger grade 3-5 diabetic foot treated with vacuum sealing drainage (VSD) combined with transverse tibial bone transport.
METHODS: Between March 2015 and January 2018, 21 patients with refractory diabetic foot who failed conservative treatment were treated with VSD combined with transverse tibial bone transport. There were 15 males and 6 females, aged 55-88 years (mean, 65 years). The diabetes history was 8-15 years (mean, 12.2 years). The duration of diabetic foot ranged from 7 to 84 days (mean, 35.3 days). The size of diabetic foot ulcer before operation ranged from 2 cm×2 cm to 8 cm×5 cm. According to Wanger classification, 8 cases were rated as grade 3, 11 cases as grade 4, and 2 cases as grade 5. Among the 21 cases, angiography of lower extremity before operation was performed in 5 cases, CT angiography of lower extremity in 16 cases, all of which indicated that the arteries below the knee were narrowed to varying degrees and not completely blocked. Preoperative foot skin temperature was (29.28±0.77)℃, C-reactive protein was (38.03±31.23) mg/L, leukocyte count was (9.44±2.21)×10 9/L, and the visual analogue scale (VAS) score was 6.8±1.5, and ability of daily living (Barthel index) was 54.3±10.3.
RESULTS: After operation, 2 patients with Wanger grade 4 and smoking history failed treatment and had an major amputation (amputation above ankle joint) at 30 days and 45 days after operation, respectively. One patient with Wanger grade 5 and chronic heart failure died of cardiac arrest at 60 days after operation. The remaining 18 patients were followed up 6-24 months (mean, 9.2 months). The external fixator was removed at 40-62 days after operation, with an average of 46 days. All the wounds healed, with a healing time of 50-120 days (mean, 62.5 days). The pain of 18 patients' feet was relieved obviously, and there was no recurrence of ulcer in situ or other parts. There was no complication such as tibial fracture and ischemic necrosis of lower leg skin after operation. After ulcer healing, the foot skin temperature was (30.86±0.80)℃, C-reactive protein was (22.90±18.42) mg/L, VAS score was 2.4±1.2, and Barthel index was 77.3±4.6, all showing significant differences when compared with preoperative ones ( P<0.05); the leukocyte count was (8.91±1.72)×10 9/L, showing no significant difference ( t=1.090, P=0.291).
CONCLUSION: VSD combined with transverse tibial bone transport can effectively promote the healing of Wanger grade 3-5 diabetic foot wounds, but smokers, unstable blood glucose control, and chronic heart failure patients have the risk of failure.

Entities:  

Keywords:  Diabetic foot; Ilizarov technique; transverse tibial bone transport; vacuum sealing drainage; wound repair

Mesh:

Year:  2020        PMID: 32666730      PMCID: PMC8180418          DOI: 10.7507/1002-1892.201911150

Source DB:  PubMed          Journal:  Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi        ISSN: 1002-1892


  21 in total

1.  The diagnosis of osteomyelitis in diabetes using erythrocyte sedimentation rate.

Authors:  Jeffrey C Karr
Journal:  J Am Podiatr Med Assoc       Date:  2002-05

2.  [Effect of vacuum sealing drainage on expressions of transforming growth factor β 1 and its receptor in diabetic foot wound].

Authors:  Chenghao Hu; Dongyu Li; Zongchao Pang; Huibin Li; Yuhui Dongye; Jiani Wu
Journal:  Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi       Date:  2018-08-15

3.  Active and passive exposure to tobacco smoke in relation to insulin sensitivity and pancreatic β-cell function in Japanese subjects.

Authors:  S Oba; E Suzuki; M Yamamoto; Y Horikawa; C Nagata; J Takeda
Journal:  Diabetes Metab       Date:  2014-10-22       Impact factor: 6.041

Review 4.  Current techniques to detect foot infection in the diabetic patient.

Authors:  Thanh Dinh; Graham Snyder; Aristidis Veves
Journal:  Int J Low Extrem Wounds       Date:  2010-03       Impact factor: 2.057

5.  Pathways to diabetic limb amputation. Basis for prevention.

Authors:  R E Pecoraro; G E Reiber; E M Burgess
Journal:  Diabetes Care       Date:  1990-05       Impact factor: 19.112

6.  Vacuum-assisted wound closure (VAC therapy) for the management of patients with high-energy soft tissue injuries.

Authors:  Dolfi Herscovici; Roy W Sanders; Julia M Scaduto; Anthony Infante; Thomas DiPasquale
Journal:  J Orthop Trauma       Date:  2003 Nov-Dec       Impact factor: 2.512

Review 7.  Diabetic foot infections: state-of-the-art.

Authors:  I Uçkay; K Gariani; Z Pataky; B A Lipsky
Journal:  Diabetes Obes Metab       Date:  2013-09-01       Impact factor: 6.577

Review 8.  Granulocyte-colony stimulating factors as adjunctive therapy for diabetic foot infections.

Authors:  Mario Cruciani; Benjamin A Lipsky; Carlo Mengoli; Fausto de Lalla
Journal:  Cochrane Database Syst Rev       Date:  2009-07-08

9.  LeucoPatch system for the management of hard-to-heal diabetic foot ulcers in the UK, Denmark, and Sweden: an observer-masked, randomised controlled trial.

Authors:  Frances Game; William Jeffcoate; Lise Tarnow; Judith L Jacobsen; Diane J Whitham; Eleanor F Harrison; Sharon J Ellender; Deborah Fitzsimmons; Magnus Löndahl
Journal:  Lancet Diabetes Endocrinol       Date:  2018-09-19       Impact factor: 32.069

10.  Incidence and Risk Factors of Diabetic Foot Ulcer: A Population-Based Diabetic Foot Cohort (ADFC Study)-Two-Year Follow-Up Study.

Authors:  Leila Yazdanpanah; Hajieh Shahbazian; Iraj Nazari; Hamid Reza Arti; Fatemeh Ahmadi; Seyed Ehsan Mohammadianinejad; Bahman Cheraghian; Saeed Hesam
Journal:  Int J Endocrinol       Date:  2018-03-15       Impact factor: 3.257

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.