Literature DB >> 32666153

Comparison of dorsal intercostal perforator artery flap and primary closure in myelomeningocele repair.

Tugay Atalay1, Kadir Oktay2, Ebru Guzel3, Lutfi Tekes4, Mehmet Solakhan5, Servet Ozkiraz6, Bahattin Celik7, Aslan Guzel8.   

Abstract

PURPOSE: Of the many suggested techniques, we used dorsal intercostal perforator artery flap (DIPAF) for the closure of myelomeningocele defects. This study compared the outcomes of primary closure and DIPAF in the closure of myelomeningoceles.
METHODS: Data of 24 patients that underwent myelomeningocele surgery at a single institution between November 2015 and September 2019 were retrospectively reviewed.
RESULTS: The primary closure group had 13 patients (54.17%) and the DIPAF group had 11 (45.83%). The mean age was 7.91 ± 13.27 days (1-60 days). Twelve patients were female and 12 were male. In 22 patients, the myelomeningocele sacs were in the lumbosacral region, while in 2, they were in the thoracolumbar region. The mean defect sizes were 14.20 ± 4.62 cm2 and 18.44 ± 3.49 cm2 in the primary closure and DIPAF groups, respectively. In each group, four patients had a kyphotic deformity. In the primary closure group, three patients had wound necrosis, two had wound dehiscence, and four had cerebrospinal fluid (CSF) leakage. In the DIPAF group, one patient had wound necrosis and one had CSF leakage. Significantly fewer complications related to the operation area were observed in the DIPAF group (p < 0.05). Increased defect size, kyphotic deformity, and presence of hydrocephalus were found to be risk factors for complications related to the operation area.
CONCLUSION: This surgical treatment protects neural tissue, prevent CSF leakage, and reduce central nervous system infection rates in myelomeningocele patients. Closure technique with the fasciocutaneous skin flap has more satisfying results than primary closure.

Entities:  

Keywords:  Dorsal intercostal perforator artery flap; Fasciocutaneous skin flap; Myelomeningocele; Open neural tube defects

Mesh:

Year:  2020        PMID: 32666153     DOI: 10.1007/s00381-020-04796-z

Source DB:  PubMed          Journal:  Childs Nerv Syst        ISSN: 0256-7040            Impact factor:   1.532


  22 in total

Review 1.  Prenatal surgery for myelomeningocele.

Authors:  William H Peranteau; N Scott Adzick
Journal:  Curr Opin Obstet Gynecol       Date:  2016-04       Impact factor: 1.927

Review 2.  Neural tube closure and neural tube defects: studies in animal models reveal known knowns and known unknowns.

Authors:  John B Wallingford
Journal:  Am J Med Genet C Semin Med Genet       Date:  2005-05-15       Impact factor: 3.908

3.  Bilobed fasciocutaneous flap closure of large meningomyeloceles.

Authors:  Bekir Atik; Onder Tan; Nejmi Kiymaz; Nebi Yilmaz; Lutfi Tekes
Journal:  Ann Plast Surg       Date:  2006-05       Impact factor: 1.539

4.  A new surgical approach to closure of large lumbosacral meningomyelocele defects.

Authors:  O M Ramirez; S S Ramasastry; M S Granick; D Pang; J W Futrell
Journal:  Plast Reconstr Surg       Date:  1987-12       Impact factor: 4.730

Review 5.  Local and regional flap closure in myelomeningocele repair: a 15-year review.

Authors:  Samuel C Lien; Cormac O Maher; Hugh J L Garton; Steven J Kasten; Karin M Muraszko; Steven R Buchman
Journal:  Childs Nerv Syst       Date:  2010-03-02       Impact factor: 1.475

6.  Meningomyelocele reconstruction with bilobed flaps.

Authors:  O Lapid; L Rosenberg; A Cohen
Journal:  Br J Plast Surg       Date:  2001-10

7.  Closure of large myelomeningocele defects using dorsal intercostal artery perforator flap.

Authors:  Daghan Isik; Lutfi Tekes; Metehan Eseoglu; Yasemin Isik; Salim Bilici; Bekir Atik
Journal:  Ann Plast Surg       Date:  2011-08       Impact factor: 1.539

Review 8.  Myelomeningocele: a review of the epidemiology, genetics, risk factors for conception, prenatal diagnosis, and prognosis for affected individuals.

Authors:  Catherine M Shaer; Nancy Chescheir; Jay Schulkin
Journal:  Obstet Gynecol Surv       Date:  2007-07       Impact factor: 2.347

9.  Large thoracolumbar meningomyelocele defects: incidence and clinical experiences with different modalities of latissimus dorsi musculocutaneus flap.

Authors:  Hamdy A El-khatib
Journal:  Br J Plast Surg       Date:  2004-07

10.  V-Y Plasty or Primary Repair Closure of Myelomeningocele: Our Experience.

Authors:  Geover Joslen Lobo; Madhukar Nayak
Journal:  J Pediatr Neurosci       Date:  2018 Oct-Dec
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