Literature DB >> 32665188

Complications in Post-mastectomy Immediate Breast Reconstruction: A Ten-year Analysis of Outcomes.

Joanna Ck Mak1, Ava Kwong2.   

Abstract

INTRODUCTION: Immediate breast reconstruction offers cosmetic and psychological advantages post-mastectomy. There are various options of reconstruction, and this study aims to evaluate the associated complications. PATIENTS AND METHODS: This is a single-center retrospective study analyzing data from January 1, 2008 to December 31, 2017 for immediate breast reconstruction procedures post-mastectomy performed at an academic breast unit. Procedures included expander and implant insertion, latissimus dorsi, pedicle transverse rectus abdominis musculocutaneous (TRAM), free TRAM, and deep inferior epigastric perforator. Complications and reoperative complications (defined as those requiring a reoperation within the first 30-day period), and associated risk factors were investigated using separate logistic regressions, and odds ratios (ORs) were calculated.
RESULTS: A total of 243 post-mastectomy immediate breast reconstruction procedures and complications rates were analyzed. The overall complication rate was 27.6%, comprised mainly of reconstruction-specific complications such as post-TRAM hernia or bulges, fat necrosis, and implant capsular contracture and leakage. The rate of reoperative complications was relatively low at 6.6%. The flap failure rate was similar between expander/implant reconstruction and autologous reconstruction methods at 3.3% and 5.6%, respectively (P = .60). Logistic regression identified significantly higher risks associated with diabetes mellitus (OR, 5.21; P = .022), obesity (OR, 5.80; P = .016), and free pedicle autologous reconstruction (OR, 3.975; P = .046) for reoperative complications.
CONCLUSION: Different methods of immediate breast reconstruction post-mastectomy are feasible and safe. However, patient variables and procedure choice should be taken into consideration when counseling patients on reconstructive options, as they are strong predictors for postoperative complications.
Copyright © 2019. Published by Elsevier Inc.

Entities:  

Keywords:  Autologous flap reconstruction; Breast cancer; Implant reconstruction; Mastectomy; Morbidity

Year:  2020        PMID: 32665188     DOI: 10.1016/j.clbc.2019.12.002

Source DB:  PubMed          Journal:  Clin Breast Cancer        ISSN: 1526-8209            Impact factor:   3.225


  2 in total

1.  Implant-based versus Autologous Reconstruction after Mastectomy for Breast Cancer: A Systematic Review and Meta-analysis.

Authors:  Justin M Broyles; Ethan M Balk; Gaelen P Adam; Wangnan Cao; Monika Reddy Bhuma; Shivani Mehta; Laura S Dominici; Andrea L Pusic; Ian J Saldanha
Journal:  Plast Reconstr Surg Glob Open       Date:  2022-03-11

2.  Repair of Breast Defect by Transfer of a Contralateral Internal Mammary Artery Perforator Flap.

Authors:  Qingfeng Yang; Zankai Wu; Xue Zhang; Juan Feng; Hengqiang Zhao; Lingxia Liao; Le Cui; Yiping Gong
Journal:  Plast Reconstr Surg Glob Open       Date:  2022-01-12
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.