Literature DB >> 32663018

Enantioselective [4 + 2] Cycloaddition Reaction of Vinylquinolines with Dienals Enabled by Synergistic Organocatalysis.

Jing Chen1,2, Yiwei Fu1, Yang Yu1, Jian-Rong Wang2, Yue-Wei Guo2, Hao Li1, Wei Wang1,3.   

Abstract

An unprecedented organocatalytic enantioselective [4 + 2] cycloaddition reaction of vinyl quinolines with dienals is achieved with the synergistic activation of CH3SO3H and a chiral aminocatalyst. The power of the process is demonstrated by its high efficiency of the production of new synthetically and biologically valued chiral quinoline architectures in high yields and with excellent enantioselectivities.

Entities:  

Year:  2020        PMID: 32663018     DOI: 10.1021/acs.orglett.0c02137

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

1.  Vinylazaarenes as dienophiles in Lewis acid-promoted Diels-Alder reactions.

Authors:  Anna E Davis; Jared M Lowe; Michael K Hilinski
Journal:  Chem Sci       Date:  2021-11-24       Impact factor: 9.825

Review 2.  Synergistic Strategies in Aminocatalysis.

Authors:  Antonio Del Vecchio; Arianna Sinibaldi; Valeria Nori; Giuliana Giorgianni; Graziano Di Carmine; Fabio Pesciaioli
Journal:  Chemistry       Date:  2022-07-04       Impact factor: 5.020

  2 in total

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