Literature DB >> 32662667

Biological significance of piRNA in liver cancer: a review.

Jiamin Xu1, Xi Yang2, Qing Zhou3, Jing Zhuang1, Shuwen Han2.   

Abstract

Liver cancer is one of the most common and deadly cancers in the world. In recent years, non-coding RNA has been a hot topic in liver cancer research. piRNAs (PIWI-interacting RNAs) are a new type of small non-coding RNA, which are formed by the PIWI proteins interacting with RNA. The latest research shows that piRNA and PIWI proteins are abnormally expressed in various cancers, including pancreatic, colorectal, breast, etc. piRNA plays an important regulatory role in liver cancer. In this review, we discuss the biological function of piRNAs and new progress in the development of liver cancer, and new targets and ideas for piRNA and PIWI proteins in the diagnosis and treatment of liver cancer.

Entities:  

Keywords:  Liver cancer; PIWI protein; piRNA

Mesh：

Substances：

Year:  2020        PMID： 32662667     DOI： 10.1080/1354750X.2020.1794041

Source DB:  PubMed          Journal:  Biomarkers        ISSN： 1354-750X            Impact factor:   2.658


  5 in total

Review 1.  Computational Methods and Online Resources for Identification of piRNA-Related Molecules.

Authors:  Yajun Liu; Aimin Li; Guo Xie; Guangming Liu; Xinhong Hei
Journal:  Interdiscip Sci       Date:  2021-04-22       Impact factor: 2.233

Review 2.  The Emerging Role of Non-Coding RNAs in Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells.

Authors:  Xiaoying Chen; Wei Xie; Ming Zhang; Yuhan Shi; Shaofen Xu; Haoyu Cheng; Lihong Wu; Janak L Pathak; Zhichao Zheng
Journal:  Front Cell Dev Biol       Date:  2022-05-16

Review 3.  A Review of Discovery Profiling of PIWI-Interacting RNAs and Their Diverse Functions in Metazoans.

Authors:  Songqian Huang; Kazutoshi Yoshitake; Shuichi Asakawa
Journal:  Int J Mol Sci       Date:  2021-10-16       Impact factor: 5.923

4.  Butorphanol Suppresses the Proliferation and Migration of Osteosarcoma by Promoting the Expression of piRNA hsa_piR_006613.

Authors:  Pengfei Cui; Deqian Xin; Fu Li; Lin Deng; Yujie Gao
Journal:  Front Oncol       Date:  2022-02-24       Impact factor: 6.244

Review 5.  PIWI interacting RNAs perspectives: a new avenues in future cancer investigations.

Authors:  Pooneh Mokarram; Maryam Niknam; Mohammadamin Sadeghdoust; Farnaz Aligolighasemabadi; Morvarid Siri; Sanaz Dastghaib; Hassan Brim; Hassan Ashktorab
Journal:  Bioengineered       Date:  2021-12       Impact factor: 3.269
  5 in total

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