Literature DB >> 32661926

Rebranding Gout: Could a Name Change for Gout Improve Adherence to Urate-Lowering Therapy?

Matthew J Coleshill1,2, Eindra Aung3,4, Jane E Carland3,4, Kate Faasse5, Sophie Stocker3,4, Richard O Day3,4.   

Abstract

Gout is the most common form of inflammatory arthritis in men, yet both patients and the public often do not recognise gout as a form of arthritis. Instead, due to historical misconceptions, gout is typically seen as a lifestyle disease caused by poor diet. In reality, there are a number of risk factors that contribute to gout, including genetic factors. Views of gout as precipitated by lifestyle alone can lead to stigma, and maladaptive beliefs that it should be treated primarily through dietary changes. This is thought to contribute to poor uptake of, and adherence to, effective pharmaceutical treatments. Gout has some of the poorest medication adherence rates of any chronic disease, contributing to suboptimal health outcomes for patients. Recent research suggests that when gout is referred to as 'urate crystal arthritis' (a rarely used name for gout), the perception of the disease by members of the public was more accurate. It was viewed as being less under personal control (i.e. less appropriately managed by behaviours such as dietary intake), and more appropriately managed by long-term medical treatment. This finding raises the possibility that patients themselves might also benefit from gout being explicitly labelled as arthritis. Indeed, parallels can be drawn between this case and other diseases that have recently had their names changed to improve outcomes, namely primary biliary cirrhosis and schizophrenia. A movement away from the term gout may benefit those living with the disease by changing illness perceptions and increasing uptake of, and adherence to, guideline-recommended treatment(s).

Entities:  

Keywords:  Allopurinol; Gout; Name change; Treatment adherence; Urate crystal arthritis; Urate-lowering therapy

Mesh:

Substances:

Year:  2020        PMID: 32661926     DOI: 10.1007/s43441-020-00198-0

Source DB:  PubMed          Journal:  Ther Innov Regul Sci        ISSN: 2168-4790            Impact factor:   1.778


  26 in total

Review 1.  Global epidemiology of gout: prevalence, incidence and risk factors.

Authors:  Chang-Fu Kuo; Matthew J Grainge; Weiya Zhang; Michael Doherty
Journal:  Nat Rev Rheumatol       Date:  2015-07-07       Impact factor: 20.543

2.  Inflammation and tissue damage in crystal deposition diseases.

Authors:  Nicola Dalbeth; Dorian O Haskard
Journal:  Curr Opin Rheumatol       Date:  2005-05       Impact factor: 5.006

Review 3.  An update on the genetics of hyperuricaemia and gout.

Authors:  Tanya J Major; Nicola Dalbeth; Eli A Stahl; Tony R Merriman
Journal:  Nat Rev Rheumatol       Date:  2018-06       Impact factor: 20.543

4.  Clinical efficacy and safety of successful longterm urate lowering with febuxostat or allopurinol in subjects with gout.

Authors:  Michael A Becker; H Ralph Schumacher; Patricia A MacDonald; Eric Lloyd; Christopher Lademacher
Journal:  J Rheumatol       Date:  2009-03-13       Impact factor: 4.666

5.  Comparison of drug adherence rates among patients with seven different medical conditions.

Authors:  Becky A Briesacher; Susan E Andrade; Hassan Fouayzi; K Arnold Chan
Journal:  Pharmacotherapy       Date:  2008-04       Impact factor: 4.705

Review 6.  Gout: why is this curable disease so seldom cured?

Authors:  Michael Doherty; Tim L Jansen; George Nuki; Eliseo Pascual; Fernando Perez-Ruiz; Leonardo Punzi; Alexander K So; Thomas Bardin
Journal:  Ann Rheum Dis       Date:  2012-08-03       Impact factor: 19.103

7.  Tophi and frequent gout flares are associated with impairments to quality of life, productivity, and increased healthcare resource use: Results from a cross-sectional survey.

Authors:  Puja P Khanna; George Nuki; Thomas Bardin; Anne-Kathrin Tausche; Anna Forsythe; Amir Goren; Jeffrey Vietri; Dinesh Khanna
Journal:  Health Qual Life Outcomes       Date:  2012-09-22       Impact factor: 3.186

Review 8.  A concise history of gout and hyperuricemia and their treatment.

Authors:  George Nuki; Peter A Simkin
Journal:  Arthritis Res Ther       Date:  2006-04-12       Impact factor: 5.156

Review 9.  "Clinical features of women with gout arthritis." A systematic review.

Authors:  K J M Jansen Dirken-Heukensfeldt; T A M Teunissen; H van de Lisdonk; A L M Lagro-Janssen
Journal:  Clin Rheumatol       Date:  2010-01-19       Impact factor: 2.980

10.  Rising burden of gout in the UK but continuing suboptimal management: a nationwide population study.

Authors:  Chang-Fu Kuo; Matthew J Grainge; Christian Mallen; Weiya Zhang; Michael Doherty
Journal:  Ann Rheum Dis       Date:  2014-01-15       Impact factor: 19.103

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.