Literature DB >> 32661033

Inappropriate Antibiotic Allergy Documentation in Health Records: A Qualitative Study on Family Physicians' and Pharmacists' Experiences.

Kitty De Clercq1, Jochen W L Cals1, Eefje G P M de Bont2.   

Abstract

PURPOSE: It is hypothesized that 90% of antibiotic allergies documented in patients' health records are not actual, potentially life threatening, type I allergies mediated by IgE. This distinction is important because such documentation increases antibiotic resistance, as more second-choice and broad-spectrum antibiotics are then used. Evidence is lacking regarding causes of this inappropriate documentation. To develop interventions aimed at improving documentation, we explored experiences of family physicians and pharmacists in this area.
METHODS: We conducted a qualitative study among family physicians and pharmacists using focus group discussions, based on purposeful sampling and a naturalistic approach. Discussions were audio-recorded, transcribed verbatim, and analyzed in duplicate by means of constant comparative technique.
RESULTS: We conducted 4 focus group discussions among 34 family physicians and 10 pharmacists, from which 3 main themes emerged: (1) magnitude and awareness of the problem of inappropriate antibiotic allergy documentation, (2) origin of the problem, and (3) approaches for addressing the problem. Participants noted that the magnitude of contamination of medical files with inappropriate documentation leads to skepticism about current documentation. Major hindering factors are electronic health record systems and electronic communication. In addition, family physicians and pharmacists believed they had insufficient knowledge about antibiotic allergies and called for tools to rectify inappropriate allergy documentation and facilitate proper documentation going forward.
CONCLUSIONS: Family physicians and pharmacists perceive that few documented antibiotic allergies are in fact correct. Electronic health record barriers and communication barriers, as well as a lack of knowledge and facilitating tools, are main causes for numerous inappropriately documented antibiotic allergies and therefore targets for improving documentation in the future.
© 2020 Annals of Family Medicine, Inc.

Entities:  

Keywords:  antibiotic allergy; antibiotic resistance; documentation; drug-related side effects and adverse reactions; electronic health records; health information technology; inappropriate registration; practice-based research; primary care; qualitative research

Mesh:

Substances:

Year:  2020        PMID: 32661033      PMCID: PMC7358028          DOI: 10.1370/afm.2537

Source DB:  PubMed          Journal:  Ann Fam Med        ISSN: 1544-1709            Impact factor:   5.166


  16 in total

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Authors:  Jakob E Borch; Klaus E Andersen; C Bindslev-Jensen
Journal:  Basic Clin Pharmacol Toxicol       Date:  2006-04       Impact factor: 4.080

3.  Impact of Reported Beta-Lactam Allergy on Inpatient Outcomes: A Multicenter Prospective Cohort Study.

Authors:  Derek R MacFadden; Anthony LaDelfa; Jessica Leen; Wayne L Gold; Nick Daneman; Elizabeth Weber; Ibrahim Al-Busaidi; Dan Petrescu; Ilana Saltzman; Megan Devlin; Nisha Andany; Jerome A Leis
Journal:  Clin Infect Dis       Date:  2016-07-11       Impact factor: 9.079

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Journal:  Drug Ther Bull       Date:  2017-03

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Journal:  BMJ       Date:  1995-07-29

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7.  Documentation of penicillin adverse drug reactions in electronic health records: inconsistent use of allergy and intolerance labels.

Authors:  Joshua M Inglis; Gillian E Caughey; William Smith; Sepehr Shakib
Journal:  Intern Med J       Date:  2017-11       Impact factor: 2.048

8.  Patient and Primary Care Physician Perceptions of Penicillin Allergy Testing and Subsequent Use of Penicillin-Containing Antibiotics: A Qualitative Study.

Authors:  Marta Wanat; Sibyl Anthierens; Christopher C Butler; Louise Savic; Sinisa Savic; Sue H Pavitt; Jonathan A T Sandoe; Sarah Tonkin-Crine
Journal:  J Allergy Clin Immunol Pract       Date:  2019-03-12

9.  The High Impact of Penicillin Allergy Registration in Hospitalized Patients.

Authors:  Savannah M van Dijk; Helga Gardarsdottir; Marjan W M Wassenberg; Jan Jelrik Oosterheert; Mark C H de Groot; Heike Rockmann
Journal:  J Allergy Clin Immunol Pract       Date:  2016-04-28

10.  Effect of a drug allergy educational program and antibiotic prescribing guideline on inpatient clinical providers' antibiotic prescribing knowledge.

Authors:  Kimberly G Blumenthal; Erica S Shenoy; Shelley Hurwitz; Christy A Varughese; David C Hooper; Aleena Banerji
Journal:  J Allergy Clin Immunol Pract       Date:  2014-04-24
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  4 in total

1.  A Continuing Education Activity Durably Addressed Knowledge Gaps Related to Penicillin Allergies Among Pharmacists and Pharmacy Technicians.

Authors:  Elizabeth W Covington; Spencer H Durham; Christopher M Bland; P Brandon Bookstaver; Elias B Chahine; Jonathan C Cho; Fernando Diggs; Bruce M Jones; Jeffrey A Kyle; Kayla R Stover; Jamie L Wagner; Peter J Hughes
Journal:  J Pharm Technol       Date:  2021-12-21

Review 2.  The Use of Electronic Health Records to Study Drug-Induced Hypersensitivity Reactions from 2000 to 2021: A Systematic Review.

Authors:  Fatima Bassir; Sheril Varghese; Liqin Wang; Yen Po Chin; Li Zhou
Journal:  Immunol Allergy Clin North Am       Date:  2022-03-31       Impact factor: 3.152

3.  Cues to improve antibiotic-allergy registration: A mixed-method study.

Authors:  Martijn Sijbom; Karolina K Braun; Frederike L Büchner; Leti van Bodegom-Vos; Bart J C Hendriks; Mark G J de Boer; Mattijs E Numans; Merel M C Lambregts
Journal:  PLoS One       Date:  2022-04-07       Impact factor: 3.240

4.  Implementing a new antibiotic allergy protocol in clinical practice: well-trusted but not used.

Authors:  P Hanssen; C Nieuwhof; S van Mens; A van de Plas; K Horstman
Journal:  JAC Antimicrob Resist       Date:  2021-06-15
  4 in total

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