Ricardo L L Dolci1, Ana Carolina Mayor de Carvalho2, Jeniffer Cristina Kozechen Rickli2, Jamile Lopes de Souza2, Williams Escalante Encinas3, José Eduardo Lutaif Dolci2, Américo Rubens Leite Dos Santos4, Paulo Roberto Lazarini5. 1. Department of Otolaryngology, Department of Surgery at Santa Casa de Misericórdia of São Paulo and College of Medical Sciences at Santa Casa of SP, São Paulo, Brazil; Skull Base Surgery Center, Santa Casa de São Paulo, São Paulo, Brazil. Electronic address: landini37@hotmail.com. 2. Department of Otolaryngology, Department of Surgery at Santa Casa de Misericórdia of São Paulo and College of Medical Sciences at Santa Casa of SP, São Paulo, Brazil. 3. Discipline of Neurosurgery, Department of Surgery at Santa Casa de Misericórdia of São Paulo and College of Medical Sciences at Santa Casa of SP, São Paulo, Brazil. 4. Discipline of Neurosurgery, Department of Surgery at Santa Casa de Misericórdia of São Paulo and College of Medical Sciences at Santa Casa of SP, São Paulo, Brazil; Skull Base Surgery Center, Santa Casa de São Paulo, São Paulo, Brazil. 5. Department of Otolaryngology, Department of Surgery at Santa Casa de Misericórdia of São Paulo and College of Medical Sciences at Santa Casa of SP, São Paulo, Brazil; Skull Base Surgery Center, Santa Casa de São Paulo, São Paulo, Brazil.
Abstract
OBJECTIVE: To determine the impact of endonasal endoscopic access to the skull base on the olfaction sense, involving the harvest of a nasoseptal flap, with the removal of the middle nasal turbinate. METHODS: A study was performed on a prospective cohort of 50 patients who underwent transnasal endoscopic surgery of the anterior skull base, with the harvest of a nasoseptal and reverse flap. The patients were divided into 2 groups: partial unilateral removal of the middle nasal turbinate and bilateral removal. Connecticut Chemosensory Clinical Research Center tests were administered before surgery and in months 1, 3, and 6 after surgery. RESULTS: There was no difference in the olfactory sense, when comparing the partial removal of the middle nasal turbinate and the bilateral removal, as well as when comparing the side without the middle nasal turbinate and the side with this structure preserved. There was a worsening in olfaction (P < 0.001) in months 1 and 3 after surgery, returning to baseline in month 6 (P > 0.05). CONCLUSIONS: Bilateral removal of the middle nasal turbinate, compared with unilateral resection, showed no impact on the olfactory function 6 months after surgery. In both groups, there was a transitory decrease in the first month, but this normalized by the sixth postoperative month.
OBJECTIVE: To determine the impact of endonasal endoscopic access to the skull base on the olfaction sense, involving the harvest of a nasoseptal flap, with the removal of the middle nasal turbinate. METHODS: A study was performed on a prospective cohort of 50 patients who underwent transnasal endoscopic surgery of the anterior skull base, with the harvest of a nasoseptal and reverse flap. The patients were divided into 2 groups: partial unilateral removal of the middle nasal turbinate and bilateral removal. Connecticut Chemosensory Clinical Research Center tests were administered before surgery and in months 1, 3, and 6 after surgery. RESULTS: There was no difference in the olfactory sense, when comparing the partial removal of the middle nasal turbinate and the bilateral removal, as well as when comparing the side without the middle nasal turbinate and the side with this structure preserved. There was a worsening in olfaction (P < 0.001) in months 1 and 3 after surgery, returning to baseline in month 6 (P > 0.05). CONCLUSIONS: Bilateral removal of the middle nasal turbinate, compared with unilateral resection, showed no impact on the olfactory function 6 months after surgery. In both groups, there was a transitory decrease in the first month, but this normalized by the sixth postoperative month.