Élyse Caron-Beaudoin1,2,3,4, Kristina W Whitworth5,6, Delphine Bosson-Rieutort7,8,9, Gilles Wendling10, Suyang Liu11,12, Marc-André Verner11,7. 1. Department of Occupational and Environmental Health, School of Public Health, Université de Montréal, 2375 Chemin de la Cote-Sainte-Catherine, Montreal, QC, Canada. elyse.caronbeaudoin@utoronto.ca. 2. Centre de recherche en santé publique, Université de Montréal et CIUSSS du Centre-Sud-de-l'Île-de-Montréal, 7101, Parc Ave., Montreal, QC, Canada. elyse.caronbeaudoin@utoronto.ca. 3. Centre for Clinical Epidemiology and Evaluation, University of British Columbia, Vancouver Coastal Health Research Institute, 828 West 10th Avenue, Research Pavilion, Vancouver, BC, Canada. elyse.caronbeaudoin@utoronto.ca. 4. Department of Health and Society and Department of Environmental and Physical Sciences, University of Toronto Scarborough, Toronto, ON, Canada. elyse.caronbeaudoin@utoronto.ca. 5. Department of Medicine, Epidemiology and Population Sciences Section, Baylor College of Medicine, Houston, TX, USA. 6. Center for Precision Environmental Health, Baylor College of Medicine, Houston, TX, USA. 7. Centre de recherche en santé publique, Université de Montréal et CIUSSS du Centre-Sud-de-l'Île-de-Montréal, 7101, Parc Ave., Montreal, QC, Canada. 8. Department of Health Policy, Management & Evaluation (DGEPS), School of Public Health, Université de Montréal, 7101 Avenue du Parc, H3N 1×9, Montreal, QC, Canada. 9. National Institute for Excellence in Health and Social Services (INESS), Information Management Team, 202 Avenue Union, Montreal, QC, Canada. 10. GW Solutions, Inc., 201-5180 Dublin Way, Nanaimo, BC, Canada. 11. Department of Occupational and Environmental Health, School of Public Health, Université de Montréal, 2375 Chemin de la Cote-Sainte-Catherine, Montreal, QC, Canada. 12. Department of Global Health, School of Health Sciences, Wuhan University, 115# Donghu Road, Wuhan, China.
Abstract
BACKGROUND: Hydraulic fracturing, a method used in Northeastern British Columbia (Canada) to extract natural gas, can release contaminants with potential deleterious health effects on fetal development. To date, the association between hydraulic fracturing activity and birth outcomes has not been evaluated in this region. OBJECTIVE: To evaluate the association between the hydraulic fracturing well density/proximity and birth outcomes (birthweight, head circumference, preterm birth and small for gestational age (SGA)). METHODS: We used birth records from the Fort St John hospital between December 30, 2006 and December 29, 2016 (n = 6333 births). To estimate gestational exposure, we used inverse distance weighting (IDW) to calculate the density/proximity of hydraulic fracturing wells to pregnant women's postal code centroid. For each birth, we calculated three IDWs using 2.5, 5, and 10 km buffer zones around women's postal code centroid. We used linear and logistic regressions to evaluate associations between quartiles of postal code well density/proximity and birth outcomes, controlling for relevant covariates. RESULTS: No associations were found between postal code well density/proximity and head circumference or SGA. A negative association was found between postal code well density/proximity and birthweight for infants born to women in the 2nd quartile of the 10 km buffer (β [95% confidence interval (CI)]: -47.28 g [-84.30; -10.25]), and in the 2nd (β [95% CI]: -40.87 g [-78.01; -3.73]) and 3rd (β [95% CI]: -42.01 g [-79.15; -4.87]) quartiles of the 5 km buffer. Increased odds of preterm birth were observed among women in the 2nd quartile of the 2.5 km buffer (odds ratio (OR) [95% CI]: 1.60 [1.30; 2.43]). CONCLUSIONS: This is the first epidemiological study in Northeastern British Columbia evaluating associations between hydraulic fracturing and health outcomes. Our results show inconsistent patterns of association between hydraulic fracturing, preterm birth and reduced birthweight, and effect estimates did not match expected dose-response relationships.
BACKGROUND:Hydraulic fracturing, a method used in Northeastern British Columbia (Canada) to extract natural gas, can release contaminants with potential deleterious health effects on fetal development. To date, the association between hydraulic fracturing activity and birth outcomes has not been evaluated in this region. OBJECTIVE: To evaluate the association between the hydraulic fracturing well density/proximity and birth outcomes (birthweight, head circumference, preterm birth and small for gestational age (SGA)). METHODS: We used birth records from the Fort St John hospital between December 30, 2006 and December 29, 2016 (n = 6333 births). To estimate gestational exposure, we used inverse distance weighting (IDW) to calculate the density/proximity of hydraulic fracturing wells to pregnant women's postal code centroid. For each birth, we calculated three IDWs using 2.5, 5, and 10 km buffer zones around women's postal code centroid. We used linear and logistic regressions to evaluate associations between quartiles of postal code well density/proximity and birth outcomes, controlling for relevant covariates. RESULTS: No associations were found between postal code well density/proximity and head circumference or SGA. A negative association was found between postal code well density/proximity and birthweight for infants born to women in the 2nd quartile of the 10 km buffer (β [95% confidence interval (CI)]: -47.28 g [-84.30; -10.25]), and in the 2nd (β [95% CI]: -40.87 g [-78.01; -3.73]) and 3rd (β [95% CI]: -42.01 g [-79.15; -4.87]) quartiles of the 5 km buffer. Increased odds of preterm birth were observed among women in the 2nd quartile of the 2.5 km buffer (odds ratio (OR) [95% CI]: 1.60 [1.30; 2.43]). CONCLUSIONS: This is the first epidemiological study in Northeastern British Columbia evaluating associations between hydraulic fracturing and health outcomes. Our results show inconsistent patterns of association between hydraulic fracturing, preterm birth and reduced birthweight, and effect estimates did not match expected dose-response relationships.
Entities:
Keywords:
Birth outcomes; Hydraulic fracturing; Inverse distance weighting; Northeastern British Columbia
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