Literature DB >> 3265071

Leukocytosis induced by microinjection of endogenous pyrogen or interleukin-1 into the preoptic and anterior hypothalamus.

A Morimoto1, T Watanabe, Y Sakata, N Murakami.   

Abstract

We investigated the effect of microinjection of endogenous pyrogen or interleukin-1 (EP/IL-1) into 40 selected brain regions on the circulating leukocyte count in rabbits. The results show that injections into the rostral region of the hypothalamus, especially the preoptic and anterior hypothalamus, induce leukocytosis.

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Year:  1988        PMID： 3265071     DOI： 10.1016/0006-8993(88)90623-3

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  3 in total

Review 1.  Exposure to acute stress induces brain interleukin-1beta protein in the rat.

Authors:  K T Nguyen; T Deak; S M Owens; T Kohno; M Fleshner; L R Watkins; S F Maier
Journal:  J Neurosci       Date:  1998-03-15       Impact factor: 6.167

2.  Interleukin-1 receptor antagonist decreases the number of necrotic neurons in rats with middle cerebral artery occlusion.

Authors:  J H Garcia; K F Liu; J K Relton
Journal:  Am J Pathol       Date:  1995-11       Impact factor: 4.307

Review 3.  Neuromodulative actions of cytokines.

Authors:  C M Blatteis
Journal:  Yale J Biol Med       Date:  1990 Mar-Apr
  3 in total

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