BACKGROUND: African Americans are more likely to die from cardiovascular disease (CVD) than all other populations in the United States. Although technological advances have supported rapid growth in applying genetics/genomics to address CVD, most research has been conducted among European Americans. The lack of African American representation in genomic samples has limited progress in equitably applying precision medicine tools, which will widen CVD disparities if not remedied. PURPOSE: This report summarizes the genetic/genomic advances that inform precision health and the implications for cardiovascular disparities in African American adults. We provide nurse scientists recommendations for becoming leaders in developing precision health tools that promote population health equity. CONCLUSIONS: Genomics will continue to drive advances in CVD prevention and management, and equitable progress is imperative. Nursing should leverage the public's trust and its widespread presence in clinical and community settings to prevent the worsening of CVD disparities among African Americans.
BACKGROUND: African Americans are more likely to die from cardiovascular disease (CVD) than all other populations in the United States. Although technological advances have supported rapid growth in applying genetics/genomics to address CVD, most research has been conducted among European Americans. The lack of African American representation in genomic samples has limited progress in equitably applying precision medicine tools, which will widen CVD disparities if not remedied. PURPOSE: This report summarizes the genetic/genomic advances that inform precision health and the implications for cardiovascular disparities in African American adults. We provide nurse scientists recommendations for becoming leaders in developing precision health tools that promote population health equity. CONCLUSIONS: Genomics will continue to drive advances in CVD prevention and management, and equitable progress is imperative. Nursing should leverage the public's trust and its widespread presence in clinical and community settings to prevent the worsening of CVD disparities among African Americans.
Authors: Mathew J Gregoski; Sarah G Buxbaum; Gaston Kapuku; Yanbin Dong; Haidong Zhu; Mary Davis; Kelsey Gonto; Frank A Treiber Journal: Ann Behav Med Date: 2013-06
Authors: Georg B Ehret; Alanna C Morrison; Ashley A O'Connor; Megan L Grove; Lisa Baird; Karen Schwander; Alan Weder; Richard S Cooper; D C Rao; Steven C Hunt; Eric Boerwinkle; Aravinda Chakravarti Journal: Eur J Hum Genet Date: 2008-06-04 Impact factor: 4.246
Authors: Peter M Visscher; Naomi R Wray; Qian Zhang; Pamela Sklar; Mark I McCarthy; Matthew A Brown; Jian Yang Journal: Am J Hum Genet Date: 2017-07-06 Impact factor: 11.025
Authors: Janet K Williams; Vence L Bonham; Catherine Wicklund; Bernice Coleman; Jacquelyn Y Taylor; Ann K Cashion Journal: Nurs Outlook Date: 2019-06-18 Impact factor: 3.315
Authors: Mariann R Piano; Nancy T Artinian; Holli A DeVon; Susan T Pressler; Kathleen T Hickey; Deborah A Chyun Journal: J Cardiovasc Nurs Date: 2018 Jul/Aug Impact factor: 2.083
Authors: Mary K Wojczynski; Mingyao Li; Lawrence F Bielak; Kathleen F Kerr; Alex P Reiner; Nathan D Wong; Lisa R Yanek; Liming Qu; Charles C White; Leslie A Lange; Jane F Ferguson; Jing He; Taylor Young; Thomas H Mosley; Jennifer A Smith; Brian G Kral; Xiuqing Guo; Quenna Wong; Santhi K Ganesh; Susan R Heckbert; Michael E Griswold; Daniel H O'Leary; Matthew Budoff; J Jeffrey Carr; Herman A Taylor; David A Bluemke; Serkalem Demissie; Shih-Jen Hwang; Dina N Paltoo; Joseph F Polak; Bruce M Psaty; Diane M Becker; Michael A Province; Wendy S Post; Christopher J O'Donnell; James G Wilson; Tamara B Harris; Maryam Kavousi; L Adrienne Cupples; Jerome I Rotter; Myriam Fornage; Lewis C Becker; Patricia A Peyser; Ingrid B Borecki; Muredach P Reilly Journal: BMC Med Genet Date: 2013-07-19 Impact factor: 2.103