Literature DB >> 32648979

Productivity costs associated with metastatic breast cancer in younger, midlife, and older women.

Justin G Trogdon1,2,3, Xuejun Liu1, Katherine E Reeder-Hayes2,4, Jason Rotter1, Donatus U Ekwueme5, Stephanie B Wheeler1,2,3.   

Abstract

BACKGROUND: The objective of the current study was to estimate productivity costs due to metastatic breast cancer (mBC) via productive time lost among survivors and potential life-years lost from premature mortality among 3 age groups: younger (aged 18-44 years), midlife (aged 45-64 years), and older (aged ≥65 years) women.
METHODS: The authors estimated the number of work and home productivity days missed due to mBC by age group using data from the 2000 to 2016 National Health Interview Survey. Years of potential life lost (YPLL) due to mBC were calculated for each age group using 2015 National Vital Statistics System data. The authors valued both sources of lost productivity time using the Current Population Survey and prior studies.
RESULTS: The per-woman value of lost productive days (work and home) due to mBC ranged from $680 for older women to $5169 for younger women. In 2015, the value of lost work and home productivity days associated with mBC nationally was $67 million for younger women, $246 million for midlife women, and $66 million for older women. YPLL were highest among midlife women (403,786 life-years), followed by older women (248,522 life-years) and younger women (95,943 life-years). Midlife women were found to have the highest market value of YPLL ($4.1 billion), followed by younger women ($1.6 billion) and older women ($527 million).
CONCLUSIONS: The results of the current study demonstrated that mBC generates a high economic burden through lost productivity, especially among midlife women.
© 2020 American Cancer Society.

Entities:  

Keywords:  breast cancer; economic burden; metastatic; productivity costs; years of potential life lost

Mesh:

Year:  2020        PMID: 32648979      PMCID: PMC7721964          DOI: 10.1002/cncr.33077

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.921


  32 in total

Review 1.  Quality of life, fertility concerns, and behavioral health outcomes in younger breast cancer survivors: a systematic review.

Authors:  Jessica Howard-Anderson; Patricia A Ganz; Julienne E Bower; Annette L Stanton
Journal:  J Natl Cancer Inst       Date:  2012-01-23       Impact factor: 13.506

Review 2.  Extending survival with chemotherapy in metastatic breast cancer.

Authors:  Joyce O'Shaughnessy
Journal:  Oncologist       Date:  2005

3.  United States Life Tables, 2015.

Authors:  Elizabeth Arias; Jiaquan Xu
Journal:  Natl Vital Stat Rep       Date:  2018-11

4.  Health and economic impact of breast cancer mortality in young women, 1970-2008.

Authors:  Donatus U Ekwueme; Gery P Guy; Sun Hee Rim; Arica White; Ingrid J Hall; Temeika L Fairley; Hazel D Dean
Journal:  Am J Prev Med       Date:  2014-01       Impact factor: 5.043

5.  Can cancer care costs impact quality of life outcomes for the entire household?

Authors:  Jason S Rotter; Jennifer C Spencer; Stephanie B Wheeler
Journal:  Psychooncology       Date:  2019-02-08       Impact factor: 3.894

6.  Years of potential life lost and productivity costs because of cancer mortality and for specific cancer sites where human papillomavirus may be a risk factor for carcinogenesis-United States, 2003.

Authors:  Donatus U Ekwueme; Harrell W Chesson; Kevin B Zhang; Appathurai Balamurugan
Journal:  Cancer       Date:  2008-11-15       Impact factor: 6.860

7.  Productivity Costs Associated With Breast Cancer Among Survivors Aged 18-44 Years.

Authors:  Donatus U Ekwueme; Justin G Trogdon; Olga A Khavjou; Gery P Guy
Journal:  Am J Prev Med       Date:  2016-02       Impact factor: 5.043

8.  Breast Cancer in Young Women: Health State Utility Impacts by Race/Ethnicity.

Authors:  Justin G Trogdon; Donatus U Ekwueme; Linda Chamiec-Case; Gery P Guy
Journal:  Am J Prev Med       Date:  2016-02       Impact factor: 5.043

9.  Do young breast cancer patients have worse outcomes?

Authors:  Melinda A Maggard; Jessica B O'Connell; Karen E Lane; Jerome H Liu; David A Etzioni; Clifford Y Ko
Journal:  J Surg Res       Date:  2003-07       Impact factor: 2.192

10.  Financial Insolvency as a Risk Factor for Early Mortality Among Patients With Cancer.

Authors:  Scott D Ramsey; Aasthaa Bansal; Catherine R Fedorenko; David K Blough; Karen A Overstreet; Veena Shankaran; Polly Newcomb
Journal:  J Clin Oncol       Date:  2016-01-25       Impact factor: 44.544

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  2 in total

1.  Projecting the Prevalence and Costs of Metastatic Breast Cancer From 2015 through 2030.

Authors:  Anagha Gogate; Stephanie B Wheeler; Katherine E Reeder-Hayes; Donatus U Ekwueme; Temeika L Fairley; Sarah Drier; Justin G Trogdon
Journal:  JNCI Cancer Spectr       Date:  2021-07-13

2.  Correlation between work productivity loss and EORTC QLQ-C30 and -BR23 domains from the MONALEESA-7 trial of premenopausal women with HR+/HER2- advanced breast cancer.

Authors:  Debu Tripathy; Tristan Curteis; Sara Hurvitz; Denise Yardley; Fabio Franke; K Govind Babu; Paul Wheatley-Price; Young-Hyuck Im; Radost Pencheva; Lucy A Eddowes; Pierre-Alexandre Dionne; David Chandiwana; Purnima Pathak; Brad Lanoue; Nadia Harbeck
Journal:  Ther Adv Med Oncol       Date:  2022-02-28       Impact factor: 8.168

  2 in total

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