Literature DB >> 32648421

Transition from open partial nephrectomy directly to robotic surgery: experience of a single surgeon to achieve "TRIFECTA".

Tiago Mendonça Lopez Castilho1, Gustavo Caserta Lemos1, Jonathan Doyun Cha1, José Roberto Colombo1, Oliver Rojas Claros1, Maria Beatriz Lemos1, Arie Carneiro1.   

Abstract

INTRODUCTION: Recent data suggest that robotic platform has become the most accessible minimal invasive surgery even for surgeons without previous training in laparoscopy. Laparoscopic partial nephrectomy (LPN) is a well-stablished procedure, however, with high level of complexity and long learning curve that limit its use.
OBJECTIVE: To describe safety, efficiency and learning curve of a single surgeon without previous experience in LPN to reach "TRIFECTA" at robot-assisted partial nephrectomy (RAPN). PATIENTS AND METHODS: This is a retrospective study, with prospective data collection of 101 patients submitted to RAPN by a single surgeon. In order to analyze the learning curve, sample was chronologically divided in two phases: first phase: P1: 50 first patients, second phase: P2: 51 subsequent patients. TRIFECTA was defined as: ischemia time lower than 25 minutes, negative surgical margin and absence of severe complications (Clavien >2).
RESULTS: Mean age of patients was 54 years (SD=11.85), median tumor size was 32mm (SD=17) and surgery was performed with zero ischemia time in 33.6% of patients (29.8% at P1 and 40.9% at P2). Demographic data of patients were similar between both groups, except tumor size (P1=27.5mm vs. P2=35.3mm; p=0.02) and body mass index (BMI) (P1=26.6kg/m2 vs. P2=29kg/m2; p=0.03). Rate of bleeding, surgical time, presence of positive margin and peri-operatory surgical complications were similar in both phases. TRIFECTA was higher in P2 in relation to P1 (P1: 58% vs. P2: 87.8%; p=0.002) and median time of hot ischemia was significantly lower at P2 (P1: 17.3 vs. P2: 11.7; p=0.02). At multivariate analysis independent factors related to TRIFECTA included: chronological phase (OR 10.74; 95% IC: 1.63-70.53; p=0.013) and tumor size (OR 0.95; 95% IC: 0.91-0.99; p=0.024).
CONCLUSION: RAPN seems to be safe and efficient with good functional and oncological results (TRIFECTA) since the beginning. Experience improvement was related to treatment of larger tumors, higher proportion of patients with zero ischemia and higher rate of TRIFECTA. Copyright® by the International Brazilian Journal of Urology.

Entities:  

Keywords:  ; Robotics; Carcinoma, Renal Cell; Kidney Neoplasms

Mesh:

Year:  2020        PMID: 32648421      PMCID: PMC7822359          DOI: 10.1590/S1677-5538.IBJU.2019.0101

Source DB:  PubMed          Journal:  Int Braz J Urol        ISSN: 1677-5538            Impact factor:   1.541


  27 in total

1.  Robotic versus laparoscopic partial nephrectomy: single-surgeon matched cohort study of 150 patients.

Authors:  Georges-Pascal Haber; Wesley M White; Sebastien Crouzet; Michael A White; Sylvain Forest; Riccardo Autorino; Jihad H Kaouk
Journal:  Urology       Date:  2010-06-19       Impact factor: 2.649

2.  Reducing warm ischaemia time during laparoscopic partial nephrectomy: a prospective comparison of two renal closure techniques.

Authors:  Hervé Baumert; Andrew Ballaro; Nimish Shah; Dhouha Mansouri; Nauman Zafar; Vincent Molinié; David Neal
Journal:  Eur Urol       Date:  2007-03-28       Impact factor: 20.096

3.  Robotic-assisted partial nephrectomy.

Authors:  Manish N Patel; Mahendra Bhandari; Mani Menon; Craig G Rogers
Journal:  BJU Int       Date:  2009-05       Impact factor: 5.588

4.  Guideline for management of the clinical T1 renal mass.

Authors:  Steven C Campbell; Andrew C Novick; Arie Belldegrun; Michael L Blute; George K Chow; Ithaar H Derweesh; Martha M Faraday; Jihad H Kaouk; Raymond J Leveillee; Surena F Matin; Paul Russo; Robert G Uzzo
Journal:  J Urol       Date:  2009-08-14       Impact factor: 7.450

5.  "Trifecta" in partial nephrectomy.

Authors:  Andrew J Hung; Jie Cai; Matthew N Simmons; Inderbir S Gill
Journal:  J Urol       Date:  2012-11-16       Impact factor: 7.450

6.  Societal costs of localized renal cancer surgery.

Authors:  Peter Chang; Peter Renehan; Kimberly N Taylor; Lauren E Dewey; Kyle C McAnally; Sara Hyde; Catrina M Crociani; Arie Carneiro; Lisa T Beaule; Andrew A Wagner
Journal:  Can J Urol       Date:  2018-08       Impact factor: 1.344

7.  Robot-assisted laparoscopic partial nephrectomy for tumors greater than 4 cm and high nephrometry score: feasibility, renal functional, and oncological outcomes with minimum 1 year follow-up.

Authors:  Gopal N Gupta; Ronald Boris; Paul Chung; W Marston Linehan; Peter A Pinto; Gennady Bratslavsky
Journal:  Urol Oncol       Date:  2011-02-02       Impact factor: 3.498

8.  Positive surgical parenchymal margin after laparoscopic partial nephrectomy for renal cell carcinoma: oncological outcomes.

Authors:  Sompol Permpongkosol; Jose R Colombo; Inderbir S Gill; Louis R Kavoussi
Journal:  J Urol       Date:  2006-12       Impact factor: 7.450

9.  Comparative analysis of laparoscopic versus open partial nephrectomy for renal tumors in 200 patients.

Authors:  Inderbir S Gill; Surena F Matin; Mihir M Desai; Jihad H Kaouk; Andrew Steinberg; Ed Mascha; Julie Thornton; Mahmoud H Sherief; Brenda Strzempkowski; Andrew C Novick
Journal:  J Urol       Date:  2003-07       Impact factor: 7.450

10.  Practice patterns and outcomes of open and minimally invasive partial nephrectomy since the introduction of robotic partial nephrectomy: results from the nationwide inpatient sample.

Authors:  Khurshid R Ghani; Shyam Sukumar; Jesse D Sammon; Craig G Rogers; Quoc-Dien Trinh; Mani Menon
Journal:  J Urol       Date:  2013-10-29       Impact factor: 7.450

View more
  4 in total

Review 1.  Nephrometry scoring systems: their importance for the planning of nephron-sparing surgery and the relationships among them.

Authors:  Victor Dubeux; José Fernando Cardona Zanier; Carolina Gianella Cobo Chantong; Fabricio Carrerette; Pedro Nicolau Gabrich; Ronaldo Damião
Journal:  Radiol Bras       Date:  2022 Jul-Aug

2.  Practical evaluation of the R.E.N.A.L. score system in 150 laparoscopic nephron sparing surgeries.

Authors:  Victor T Dubeux; José Fernando C Zanier; Pedro N Gabrich; Fabricio B Carrerette; José C A Milfont; Ronaldo Damião
Journal:  Int Braz J Urol       Date:  2022 Jan-Feb       Impact factor: 1.541

3.  Analysis of surgical and histopathological results of robot-assisted partial nephrectomy with use of three or four robotic arms: an early series results.

Authors:  Lucas Schulze; Victor Teixeira Dubeux; José C A Milfont; Gustavo Peçanha; Pedro Ferrer; Andre Guilherme Cavalcanti
Journal:  Int Braz J Urol       Date:  2022 May-Jun       Impact factor: 1.541

Review 4.  Trifecta achievement in patients undergoing partial nephrectomy: a systematic review and meta-analysis of predictive factors.

Authors:  Nigemutu Bai; Muge Qi; Dan Shan; Suo Liu; Ta Na; Liang Chen
Journal:  Int Braz J Urol       Date:  2022 Jul-Aug       Impact factor: 3.050

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.