Literature DB >> 3264789

Semiquantitative assessment of regional cerebral perfusion using 99mTc HM-PAO and emission tomography.

G Spreafico1, G Gadola, F Cammelli, P Caffarra, A Scaglioni.   

Abstract

A method for the relative quantification of 99mTc-HM-PAO distribution in brain SPECT is described. The method, applied in 12 normal volunteers and 150 patients suffering from different cerebral diseases, uses circumferential profiles to quantify the relative radionuclide distribution in the brain tomograms as an angular function with the origin at the center of the brain slice. Abnormal 99mTc-HM-PAO distribution is evaluated by comparing the count content of symmetrical selected parts of the profile curve and comparing each patient's profile with the corresponding limits of normal ones, determined from the pooled profiles of 12 normal subjects. This computerized method allows an accurate, reproducible and objective assessment of the relative HM-PAO distribution in the brain.

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Year:  1988        PMID： 3264789     DOI： 10.1007/bf00286778

Source DB:  PubMed          Journal:  Eur J Nucl Med        ISSN： 0340-6997


  8 in total

1.  Imaging of cerebral blood flow-to-volume distribution using SPECT.

Authors:  W H Knapp; R von Kummer; W Kübler
Journal:  J Nucl Med       Date:  1986-04       Impact factor: 10.057

2.  A 99Tcm-labelled radiotracer for the investigation of cerebral vascular disease.

Authors:  P J Ell; J M Hocknell; P H Jarritt; I Cullum; D Lui; D Campos-Costa; D P Nowotnik; R D Pickett; L R Canning; R D Neirinckx
Journal:  Nucl Med Commun       Date:  1985-08       Impact factor: 1.690

3.  Cerebral blood flow studies with 123iodine-labelled amines.

Authors:  P J Ell; D Lui; I Cullum; P H Jarritt; M Donaghy; M J Harrison
Journal:  Lancet       Date:  1983-06-18       Impact factor: 79.321

4.  The diagnosis of dementia with single photon emission computed tomography.

Authors:  W J Jagust; T F Budinger; B R Reed
Journal:  Arch Neurol       Date:  1987-03

5.  Quantifying local cerebral blood flow by N-isopropyl-p-[123I]iodoamphetamine (IMP) tomography.

Authors:  D E Kuhl; J R Barrio; S C Huang; C Selin; R F Ackermann; J L Lear; J L Wu; T H Lin; M E Phelps
Journal:  J Nucl Med       Date:  1982-03       Impact factor: 10.057

6.  A new brain perfusion imaging agent: [I-123]HIPDM:N,N,N'-trimethyl-N'-[2-hydroxy-3-methyl-5-iodobenzyl]-1,3-propanediamine.

Authors:  H F Kung; K M Tramposch; M Blau
Journal:  J Nucl Med       Date:  1983-01       Impact factor: 10.057

7.  Regional quantitative noninvasive assessment of cerebral perfusion and function with N-isopropyl-[123I]p-iodoamphetamine.

Authors:  G K von Schulthess; E Ketz; P A Schubiger; A Bekier
Journal:  J Nucl Med       Date:  1985-01       Impact factor: 10.057

8.  N-isopropyl-[123I] p-iodoamphetamine: single-pass brain uptake and washout; binding to brain synaptosomes; and localization in dog and monkey brain.

Authors:  H S Winchell; W D Horst; L Braun; W H Oldendorf; R Hattner; H Parker
Journal:  J Nucl Med       Date:  1980-10       Impact factor: 10.057
  8 in total
  2 in total

1.  Semi-automatic quantification of regional cerebral perfusion in primary degenerative dementia using 99m technetium-hexamethylpropylene amine oxime and single photon emission tomography.

Authors:  P Goulding; A Burjan; R Smith; R Lawson; J Snowden; B Northen; D Neary; H Testa
Journal:  Eur J Nucl Med       Date:  1990

2.  Semi-quantitative analysis of regional cerebral perfusion.

Authors:  H G Gemmell; P F Sharp
Journal:  Eur J Nucl Med       Date:  1989
  2 in total

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