Crystal M Glover1, Lei Yu2, Christopher C Stewart3, Robert S Wilson4, David A Bennett2, Patricia A Boyle5. 1. Rush Alzheimer's Disease Center, Rush University Medical Center (CMG, LY, RSW, DAB, PAB), Chicago, IL; Department of Psychiatry and Behavioral Sciences, Rush Medical College (CMG, RSW, PAB), Chicago, IL; Department of Neurological Sciences, Rush Medical College (CMG, LY, RSW, DAB), Chicago, IL. Electronic address: Crystal_Glover@rush.edu. 2. Rush Alzheimer's Disease Center, Rush University Medical Center (CMG, LY, RSW, DAB, PAB), Chicago, IL; Department of Neurological Sciences, Rush Medical College (CMG, LY, RSW, DAB), Chicago, IL. 3. Department of Neurology, Indiana University School of Medicine (CCS), Indianapolis, IN. 4. Rush Alzheimer's Disease Center, Rush University Medical Center (CMG, LY, RSW, DAB, PAB), Chicago, IL; Department of Psychiatry and Behavioral Sciences, Rush Medical College (CMG, RSW, PAB), Chicago, IL; Department of Neurological Sciences, Rush Medical College (CMG, LY, RSW, DAB), Chicago, IL. 5. Rush Alzheimer's Disease Center, Rush University Medical Center (CMG, LY, RSW, DAB, PAB), Chicago, IL; Department of Psychiatry and Behavioral Sciences, Rush Medical College (CMG, RSW, PAB), Chicago, IL.
Abstract
OBJECTIVE: The purpose of this study was to test the hypothesis that late life cognitive activity is associated with decision-making in older adults and to examine whether this association varies by level of cognitive function. DESIGN: This study employed a cross-sectional design. SETTING: All data were collected in participants' community-based residences. PARTICIPANTS: Participants were 1,084 older adults (mean age = 81.05 years, standard deviation = 7.53) without dementia (median Mini-Mental State Examination score = 29, interquartile range = 27.86-30.00). MEASUREMENTS: Participants completed assessments of late life cognitive activity, cognitive function, and decision-making. We used linear regression models to examine the associations of late life cognitive activity and cognitive function with decision-making. RESULTS: In a regression model adjusted for age, gender, and education, more frequent late life cognitive activity was associated with better decision-making, as was higher cognitive function. Furthermore, in an additional model that included the interaction of late life cognitive activity and cognitive function, the interaction was significant, such that late life cognitive activity was most strongly associated with decision-making among participants with lower levels of cognitive function. CONCLUSION: Frequent engagement in late life cognitive activity may help maintain decision-making among older persons, particularly among those with lower levels of cognitive function.
OBJECTIVE: The purpose of this study was to test the hypothesis that late life cognitive activity is associated with decision-making in older adults and to examine whether this association varies by level of cognitive function. DESIGN: This study employed a cross-sectional design. SETTING: All data were collected in participants' community-based residences. PARTICIPANTS: Participants were 1,084 older adults (mean age = 81.05 years, standard deviation = 7.53) without dementia (median Mini-Mental State Examination score = 29, interquartile range = 27.86-30.00). MEASUREMENTS: Participants completed assessments of late life cognitive activity, cognitive function, and decision-making. We used linear regression models to examine the associations of late life cognitive activity and cognitive function with decision-making. RESULTS: In a regression model adjusted for age, gender, and education, more frequent late life cognitive activity was associated with better decision-making, as was higher cognitive function. Furthermore, in an additional model that included the interaction of late life cognitive activity and cognitive function, the interaction was significant, such that late life cognitive activity was most strongly associated with decision-making among participants with lower levels of cognitive function. CONCLUSION: Frequent engagement in late life cognitive activity may help maintain decision-making among older persons, particularly among those with lower levels of cognitive function.
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