Literature DB >> 32645078

Hepatitis B screening and vaccination status of healthcare providers in Wakiso district, Uganda.

Tonny Ssekamatte1, Trasias Mukama1, Simon P S Kibira2, Rawlance Ndejjo1, Justine Nnakate Bukenya2, Zirimala Paul Alex Kimoga3, Samuel Etajak1, Rebecca Nuwematsiko1, Esther Buregyeya1, John C Ssempebwa1, John Bosco Isunju1, Richard Kibirango Mugambe1, Aisha Nalugya1, Solomon Tsebeni Wafula1, Joan Nankya Mutyoba4.   

Abstract

BACKGROUND: Screening and vaccination against Hepatitis B virus (HBV) infection remains the most effective intervention in curbing the disease. However, there is limited evidence on the factors associated with the uptake of these services in Uganda. This study determined the uptake of HBV screening and vaccination status, and associated factors among Healthcare Providers (HCPs) in Wakiso district, Uganda.
MATERIALS AND METHODS: This cross-sectional study was conducted among 306 HCPs, randomly selected from 55 healthcare facilities. Prevalence ratios (PR) were used to determine the factors associated with HBV screening and vaccination status of HCPs.
RESULTS: Of the 306 HCPs, 230 (75.2%) had ever screened for HBV infection while 177 (57.8%) were fully vaccinated. Being male was positively associated with 'ever been screened' for HBV infection (Adjusted PR = 1.27, 95%CI 1.13-1.41). Working in a public healthcare facility (Adjusted PR = 0.78, 95%CI 0.68-0.90) was negatively associated with ever been screened. Male sex (Adjusted PR = 1.21, 95%CI 1.01-1.46), the belief that the HBV vaccine was safe (Adjusted PR = 1.72, 95%CI 1.03-2.89) and ever been screened (Adjusted PR = 2.28, 95%CI 1.56-3.34) were positively associated with being fully vaccinated. However, working in a public healthcare facility (Adjusted PR = 0.79, 95%CI 0.64-0.98), self-perceived risk of HBV infection (Adjusted PR = 0.72, 95% CI:0.62-0.84), and working in a healthcare facility with infection control guidelines (Adjusted PR = 0.79, 95%CI 0.66-0.95) were negatively associated with being fully vaccinated.
CONCLUSION: Three quarters of HCPs had ever been screened for HBV while slightly more than half were fully vaccinated. HBV screening and vaccination interventions need to consider the HCP sex, risk perception, attitude towards safety and efficacy of the hepatitis B vaccine, and healthcare facility characteristics such as ownership and availability of infection control guidelines, in order to be successful.

Entities:  

Year:  2020        PMID: 32645078     DOI: 10.1371/journal.pone.0235470

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


  11 in total

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2.  Awareness of hepatitis B post-exposure prophylaxis among healthcare providers in Wakiso district, Central Uganda.

Authors:  John Bosco Isunju; Solomon Tsebeni Wafula; Rawlance Ndejjo; Rebecca Nuwematsiko; Pamela Bakkabulindi; Aisha Nalugya; James Muleme; Winnie Kansiime Kimara; Simon P S Kibira; Joana Nakiggala; Richard K Mugambe; Esther Buregyeya; Tonny Ssekamatte; Rhoda K Wanyenze
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4.  Predictors of Hepatitis B screening and vaccination status of young psychoactive substance users in informal settlements in Kampala, Uganda.

Authors:  Tonny Ssekamatte; John Bosco Isunju; Joan Nankya Mutyoba; Moses Tetui; Richard K Mugambe; Aisha Nalugya; Winnifred K Kansiime; Chenai Kitchen; Wagaba Brenda; Patience Oputan; Justine Nnakate Bukenya; Esther Buregyeya; Simon P S Kibira
Journal:  PLoS One       Date:  2022-05-19       Impact factor: 3.752

5.  A positive attitude among primary healthcare providers predicts better hepatitis B prevention practices: evidence from a cross-sectional survey in Wakiso district, Central Uganda.

Authors:  Tonny Ssekamatte; John Bosco Isunju; Paul Alex Kimoga Zirimala; Samuel Etajak; Saul Kamukama; Mathias Seviiri; Mary Nakafeero; Aisha Nalugya; Solomon Tsebeni Wafula; Edwinah Atusingwize; Justine N Bukenya; Richard K Mugambe
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Journal:  Ther Adv Vaccines Immunother       Date:  2021-07-29

7.  Assessment of Hepatitis B Vaccination Status and Associated Factors among Healthcare Workers in Bosaso, Puntland, Somalia 2020.

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Journal:  Biomed Res Int       Date:  2022-03-21       Impact factor: 3.411

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Authors:  F K Sikakulya; D K Munyambalu; S B Mambo; A K Mutsunga; S F Djuma; P A Djuna; E Ndiwelubula; W A Ngavo; S M Sahika; Patrick Kumbowi Kumbakulu; Kalima Nzanzu Adelard; T A Shindano
Journal:  Infect Prev Pract       Date:  2022-06-24

9.  Hepatitis B and C virus infection among healthcare workers in Africa: a systematic review and meta-analysis.

Authors:  Daniel Atlaw; Biniyam Sahiledengle; Zerihun Tariku
Journal:  Environ Health Prev Med       Date:  2021-06-02       Impact factor: 3.674

10.  Antibody levels and protection after Hepatitis B vaccine in adult vaccinated healthcare workers in northern Uganda.

Authors:  Moses Ocan; Frances Acheng; Carol Otike; Judith Beinomugisha; David Katete; Celestino Obua
Journal:  PLoS One       Date:  2022-01-21       Impact factor: 3.240

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