Literature DB >> 326444

Rheumatoid factor plaque-forming cells in rheumatoid synovial tissue.

M M Taylor-Upsahl, T G Abrahamsen, J B Natvig.   

Abstract

Cells producing rheumatoid factor (RF) were readily detected in vitro by means of a haemolytic plaque assay system employing sheep erythrocytes (SRBC) sensitized with reduced and alkylated rabbit IgG anti-SRBC antibody as target cells. Rheumatoid factor-producing, plaque-forming cells (RF-PFC) were observed in all of the synovial tissue cell preparations from seropositive rheumatoid arthritis patients studied. The numbers of RF-PFC varied considerably without any direct correlation with serum titres of RF antibody activity. However, high numbers of RF-PFC were never found in patients with low rheumatoid factor titres whereas, high and low numbers of RF-PFC were found among the patients with high RF titres. Synovial tissue cell preparations from a group of seronegative patients, with only one exception, failed to exhibit RF-PFC.

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Year:  1977        PMID： 326444      PMCID： PMC1540764     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  24 in total

1.  HEMOLYTIC COMPLEMENT IN SYNOVIAL FLUID.

Authors:  T J PEKIN; N J ZVAIFLER
Journal:  J Clin Invest       Date:  1964-07       Impact factor: 14.808

2.  THE DEPRESSED SYNOVIAL COMPLEMENT ACTIVITY IN ADULT AND JUVENILE RHEUMATOID ARTHRITIS.

Authors:  H HEDBERG
Journal:  Acta Rheumatol Scand       Date:  1964

3.  Effect of mercaptoethanol on complement binding ability of human 7 S gammaglobulin.

Authors:  G WIEDERMANN; P A MIESCHER; E C FRANKLIN
Journal:  Proc Soc Exp Biol Med       Date:  1963-07

4.  Plaque formation in agar by single antibody-producing cells.

Authors:  N K JERNE; A A NORDIN
Journal:  Science       Date:  1963-04-26       Impact factor: 47.728

5.  An Immunofluorescence Study of Rheumatoid Factor.

Authors:  J N McCormick
Journal:  Ann Rheum Dis       Date:  1963-01       Impact factor: 19.103

6.  Presence of aggregated gamma-G-globulin in certain rheumatoid synovial effusions.

Authors:  K Hannestad
Journal:  Clin Exp Immunol       Date:  1967-07       Impact factor: 4.330

7.  Distribution of the anti-gamma globulin factors in the synovial membrane and other tissues in various diseases.

Authors:  L Bonomo; A Tursi; U Gillardi
Journal:  Ann Rheum Dis       Date:  1968-03       Impact factor: 19.103

8.  In vitro synthesis of immunoglobulin by rheumatoid synovial membrane.

Authors:  J D Smiley; C Sachs; M Ziff
Journal:  J Clin Invest       Date:  1968-03       Impact factor: 14.808

Review 9.  Rheumatoid factor: its nature, specificity, and production in rheumatoid arthritis.

Authors:  P M Johnson; W P Faulk
Journal:  Clin Immunol Immunopathol       Date:  1976-11

10.  THE ROLE OF DISULFIDE BONDS IN THE COMPLEMENT-FIXING AND PRECIPITATING PROPERTIES OF 7S RABBIT AND SHEEP ANTIBODIES.

Authors:  P H SCHUR; G D CHRISTIAN
Journal:  J Exp Med       Date:  1964-10-01       Impact factor: 14.307
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  14 in total

Review 1.  Local immune responses in certain extra-articular manifestations of rheumatoid arthritis.

Authors:  J T Halla; R E Schrohenloher; W J Koopman
Journal:  Ann Rheum Dis       Date:  1992-05       Impact factor: 19.103

2.  The neo-synovial membrane of patients with active rheumatoid arthritis at resynovectomy. Histomorphological and immunohistological evaluations.

Authors:  J G Saal; P Fritz; B J Maschek; A Mischlinski; W Laschner
Journal:  Rheumatol Int       Date:  1990       Impact factor: 2.631

Review 3.  The B cell system in the rheumatoid inflammation. New insights into the pathogenesis of rheumatoid arthritis using synovial B cell hybridoma clones.

Authors:  J B Natvig; I Randen; K Thompson; O Førre; E Munthe
Journal:  Springer Semin Immunopathol       Date:  1989

4.  Human monoclonal rheumatoid factors derived from the polyclonal repertoire of rheumatoid synovial tissue: production and characterization.

Authors:  I Randen; K M Thompson; J B Natvig; O Førre; K Waalen
Journal:  Clin Exp Immunol       Date:  1989-10       Impact factor: 4.330

5.  Lack of hidden complement fixing IgM rheumatoid factor in adult seronegative rheumatoid arthritis.

Authors:  D L Robbins; T L Moore
Journal:  Ann Rheum Dis       Date:  1980-02       Impact factor: 19.103

6.  Evidence for B cell activation in patients with active rheumatoid arthritis.

Authors:  P Y Youinou; W L Irving; M Shipley; J Hayes; P M Lydyard
Journal:  Clin Exp Immunol       Date:  1984-01       Impact factor: 4.330

7.  Rheumatoid factors in mice: plaque assay for homophile and heterophile rheumatoid factors.

Authors:  D W Dresser; A M Popham
Journal:  Immunology       Date:  1980-11       Impact factor: 7.397

8.  Spontaneous and aggregated IgG induced rheumatoid factor producing cells in rheumatoid arthritis.

Authors:  E J Pisko; R A Turner; M Panetti; S L Foster; E Heise
Journal:  Rheumatol Int       Date:  1985       Impact factor: 2.631

9.  Pokeweed mitogen-induced secretion of IgG- and IgM-rheumatoid factors by synovial fluid and blood B lymphocytes in rheumatoid arthritis.

Authors:  J Petersen; C Heilmann; M Høier-Madsen
Journal:  Rheumatol Int       Date:  1986       Impact factor: 2.631

10.  Complement activation induced by rabbit rheumatoid factor.

Authors:  R R Meyer; J C Brown
Journal:  Infect Immun       Date:  1980-07       Impact factor: 3.441
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