Literature DB >> 3264396

Intracellular picrotoxin blocks pentobarbital-gated Cl- conductance.

N Inomata1, N Tokutomi, Y Oyama, N Akaike.   

Abstract

Using the 'inside-out' configuration of frog sensory neurons, we studied the effect of intracellular picrotoxin on the pentobarbital-gated single channel response of Cl- -current (iCl). The pentobarbital-induced iCl showed no voltage-dependency and the single channel conductance (gamma Cl) was 16 +/- 3.1 pS (n = 6). Picrotoxin caused the pentobarbital-gated Cl- channels to react in a flickering pattern and then finally caused them to cease their opening altogether. This inhibitory action of picrotoxin was reversible.

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Year:  1988        PMID： 3264396     DOI： 10.1016/0168-0102(88)90007-7

Source DB:  PubMed          Journal:  Neurosci Res        ISSN： 0168-0102            Impact factor:   3.304


  13 in total

1.  Presynaptic gating of postsynaptically expressed plasticity at mature thalamocortical synapses.

Authors:  Jay A Blundon; Ildar T Bayazitov; Stanislav S Zakharenko
Journal:  J Neurosci       Date:  2011-11-02       Impact factor: 6.167

2.  Subthreshold membrane conductances enhance directional selectivity in vertebrate sensory neurons.

Authors:  Maurice J Chacron; Eric S Fortune
Journal:  J Neurophysiol       Date:  2010-05-05       Impact factor: 2.714

3.  Amygdala inputs drive feedforward inhibition in the medial prefrontal cortex.

Authors:  Jonathan Dilgen; Hugo A Tejeda; Patricio O'Donnell
Journal:  J Neurophysiol       Date:  2013-05-08       Impact factor: 2.714

4.  Modulation of synaptic function through the α-neurexin-specific ligand neurexophilin-1.

Authors:  Gesche Born; Dorothee Breuer; Shaopeng Wang; Astrid Rohlmann; Philippe Coulon; Puja Vakili; Carsten Reissner; Friedemann Kiefer; Martin Heine; Hans-Christian Pape; Markus Missler
Journal:  Proc Natl Acad Sci U S A       Date:  2014-03-17       Impact factor: 11.205

5.  Permeability and single channel conductance of human homomeric rho1 GABAC receptors.

Authors:  V E Wotring; Y Chang; D S Weiss
Journal:  J Physiol       Date:  1999-12-01       Impact factor: 5.182

6.  Loss of MeCP2 from forebrain excitatory neurons leads to cortical hyperexcitation and seizures.

Authors:  Wen Zhang; Matthew Peterson; Barbara Beyer; Wayne N Frankel; Zhong-wei Zhang
Journal:  J Neurosci       Date:  2014-02-12       Impact factor: 6.167

7.  Closing the gate in the limbic striatum: prefrontal suppression of hippocampal and thalamic inputs.

Authors:  Gwendolyn G Calhoon; Patricio O'Donnell
Journal:  Neuron       Date:  2013-04-10       Impact factor: 17.173

Review 8.  The diversity of GABAA receptors. Pharmacological and electrophysiological properties of GABAA channel subtypes.

Authors:  W Hevers; H Lüddens
Journal:  Mol Neurobiol       Date:  1998-08       Impact factor: 5.590

9.  Bidirectional plasticity in fast-spiking GABA circuits by visual experience.

Authors:  Yoko Yazaki-Sugiyama; Siu Kang; Hideyuki Câteau; Tomoki Fukai; Takao K Hensch
Journal:  Nature       Date:  2009-11-12       Impact factor: 49.962

10.  Thalamocortical long-term potentiation becomes gated after the early critical period in the auditory cortex.

Authors:  Sungkun Chun; Ildar T Bayazitov; Jay A Blundon; Stanislav S Zakharenko
Journal:  J Neurosci       Date:  2013-04-24       Impact factor: 6.167
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