P Irimia1,2,3, M Garrido-Cumbrera4, S Santos-Lasaosa3,5,6, O Braçe4, I Colomina7, C Blanch8, P Pozo-Rosich3,9,10. 1. Neurology Department, Clínica Universidad de Navarra, Pamplona, Spain. 2. Navarra's Health Research Institute (IDISNA), Pamplona, Spain. 3. Headache Study Group of the Spanish Neurological Society (GECSEN), Madrid, Spain. 4. Health and Territory Research (HTR), Universidad de Sevilla, Sevilla, Spain. 5. Neurology, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain. 6. Instituto de Investigación Sanitaria IIS Aragón, Zaragoza, Spain. 7. President of the Spanish Patient's Association of Migraine and Headache (AEMICE), Madrid, Spain. 8. Market Access, Novartis, Barcelona, Spain. 9. Headache Unit, Neurology Department, Vall d'Hebron University Hospital, Barcelona, Spain. 10. Headache Research Group, VHIR, Universitat Autónoma de Barcelona, Barcelona, Spain.
Abstract
BACKGROUND AND PURPOSE: Migraine is a common and costly neurological disorder. The aims of this study were to quantify the costs of chronic (CM) and episodic migraine (EM) in Spain, evaluating the impact of psychiatric comorbidities and disability, and to estimate the economic savings associated with reducing the number of migraine-days by 50%. METHODS: This was an observational, cross-sectional analysis of data from migraine patients who participated in the Spanish Migraine Atlas. The participants were invited to complete a structured questionnaire including the following scales: the Headache Needs Assessment, the Hospital Anxiety and Depression Scale, and the Migraine Disability Assessment Scale (MIDAS). RESULTS: A total of 475 patients were included, of whom 187 had CM (39.4%). Total costs per patient/year were: €16 578.2 ± €34 568.1 for CM and €6227.8 ± €6515.7 for EM. A higher degree of disability, according to MIDAS, significantly increased the total cost of migraine, while the presence of psychiatric comorbidity increased costs for EM patients only. A reduction of 1 migraine-day per month decreased average total costs by €744.14 per patient/year for EM and €663.20 per patient/year for CM, while a reduction in the number of migraine-days by 50% would result in economic savings of €2232.44 per patient/year (R2 = 0.927) for EM and €6631.99 per patient/year (R2 = 0.886) for CM. CONCLUSIONS: The costs associated with migraine were driven by migraine frequency and the degree of disability, whereas psychiatric comorbidity only influenced the cost of EM. These results highlight the need to optimize migraine management to reduce the economic migraine burden. Future studies are needed to confirm our results.
BACKGROUND AND PURPOSE:Migraine is a common and costly neurological disorder. The aims of this study were to quantify the costs of chronic (CM) and episodic migraine (EM) in Spain, evaluating the impact of psychiatric comorbidities and disability, and to estimate the economic savings associated with reducing the number of migraine-days by 50%. METHODS: This was an observational, cross-sectional analysis of data from migrainepatients who participated in the Spanish Migraine Atlas. The participants were invited to complete a structured questionnaire including the following scales: the Headache Needs Assessment, the Hospital Anxiety and Depression Scale, and the Migraine Disability Assessment Scale (MIDAS). RESULTS: A total of 475 patients were included, of whom 187 had CM (39.4%). Total costs per patient/year were: €16 578.2 ± €34 568.1 for CM and €6227.8 ± €6515.7 for EM. A higher degree of disability, according to MIDAS, significantly increased the total cost of migraine, while the presence of psychiatric comorbidity increased costs for EM patients only. A reduction of 1 migraine-day per month decreased average total costs by €744.14 per patient/year for EM and €663.20 per patient/year for CM, while a reduction in the number of migraine-days by 50% would result in economic savings of €2232.44 per patient/year (R2 = 0.927) for EM and €6631.99 per patient/year (R2 = 0.886) for CM. CONCLUSIONS: The costs associated with migraine were driven by migraine frequency and the degree of disability, whereas psychiatric comorbidity only influenced the cost of EM. These results highlight the need to optimize migraine management to reduce the economic migraine burden. Future studies are needed to confirm our results.
Authors: Pablo Irimia; David García-Azorín; Mercedes Núñez; Sílvia Díaz-Cerezo; Pepa García de Polavieja; Tommaso Panni; Aram Sicras-Navarro; Antoni Sicras-Mainar; Antonio Ciudad Journal: J Headache Pain Date: 2022-07-07 Impact factor: 8.588
Authors: Peter Petschner; Daniel Baksa; Gabor Hullam; Dora Torok; Andras Millinghoffer; J F William Deakin; Gyorgy Bagdy; Gabriella Juhasz Journal: PLoS One Date: 2021-12-31 Impact factor: 3.240