Miao Liu1,2, Shanshan Yang3, Shengshu Wang3, Yali Zhao4, Qiao Zhu4, Chaoxue Ning4, Yao He5. 1. Department of Statistics and Epidemiology, Graduate School of Medical School of Chinese PLA General Hospital, 100853, Beijing, China. liumiaolmbxb@163.com. 2. Institute of Geriatrics and Beijing Key Laboratory of Normal Aging and Geriatrics, National Clinical Research Center for Geriatrics Diseases, Second Medical Center of Chinese PLA General Hospital, 100853, Beijing, China. liumiaolmbxb@163.com. 3. Institute of Geriatrics and Beijing Key Laboratory of Normal Aging and Geriatrics, National Clinical Research Center for Geriatrics Diseases, Second Medical Center of Chinese PLA General Hospital, 100853, Beijing, China. 4. Central Laboratory, Hainan Branch of Chinese People's Liberation Army General Hospital, Sanya, China. 5. Institute of Geriatrics and Beijing Key Laboratory of Normal Aging and Geriatrics, National Clinical Research Center for Geriatrics Diseases, Second Medical Center of Chinese PLA General Hospital, 100853, Beijing, China. yhe301@sina.com.
Abstract
OBJECTIVE: There was little data on the distribution of blood glucose levels and diabetes prevalence for centenarians and the oldest-old. The aim of this study is to analyzed the distribution of blood glucose and diabetes prevalence for centenarians and oldest-old in China: Based on the China Hainan Centenarian Cohort Study (CHCCS) and China Hainan Oldest-old Cohort Study (CHOCS). DESIGN: A cross-sectional study. SETTING AND PARTICIPANTS: A total of 1002 centenarians and 798 oldest-old were enrolled from 18 cities and counties in Hainan Province (one of the longevity provinces) from 2016-2018. MEASURES: The fasting blood glucose was tested and prevalence of diabetes was calculated. RESULTS: The average age of centenarians was 102.77 ± 2.55 years old, 82.0% were women. The average age of the oldest-old was 84.99 ± 4.01 years old, 59.9% were women. The average blood glucose of centenarians was 5.12 ± 1.44 and 4.80 ± 1.27 mmol/L, and more than 70% were between 3.00 mmol/L and 5.99 mmol/L. There was no statistical difference between different genders and age groups. A total of 9.5% of centenarians had diabetes and 8.1% had IFG. A total of 11.4% of the oldest-old had diabetes and 4.4% had IFG. Abdominal obesity and TG levels may be associated with diabetes prevalence. The corresponding ORs were 1.517(1.083-2.125) and 1.473(1.089-1.943) respectively of abdominal obesity among centenarians and the oldest-old respectively, and corresponding ORs 1.182(1.081-1.316) and 1.162(1.009-1.699) respectively of abdominal obesity among centenarians and the oldest-old respectively CONCLUSIONS AND IMPLICATIONS: In summary, the results based on CHCCS with the largest sample among centenarians and CHOCS showed that the blood glucose level and the prevalence of diabetes were at a lower level than those of adults or younger elderly. The results provide new evidence for target level of blood glucose control in those older elderly.
OBJECTIVE: There was little data on the distribution of blood glucose levels and diabetes prevalence for centenarians and the oldest-old. The aim of this study is to analyzed the distribution of blood glucose and diabetes prevalence for centenarians and oldest-old in China: Based on the China Hainan Centenarian Cohort Study (CHCCS) and China Hainan Oldest-old Cohort Study (CHOCS). DESIGN: A cross-sectional study. SETTING AND PARTICIPANTS: A total of 1002 centenarians and 798 oldest-old were enrolled from 18 cities and counties in Hainan Province (one of the longevity provinces) from 2016-2018. MEASURES: The fasting blood glucose was tested and prevalence of diabetes was calculated. RESULTS: The average age of centenarians was 102.77 ± 2.55 years old, 82.0% were women. The average age of the oldest-old was 84.99 ± 4.01 years old, 59.9% were women. The average blood glucose of centenarians was 5.12 ± 1.44 and 4.80 ± 1.27 mmol/L, and more than 70% were between 3.00 mmol/L and 5.99 mmol/L. There was no statistical difference between different genders and age groups. A total of 9.5% of centenarians had diabetes and 8.1% had IFG. A total of 11.4% of the oldest-old had diabetes and 4.4% had IFG. Abdominal obesity and TG levels may be associated with diabetes prevalence. The corresponding ORs were 1.517(1.083-2.125) and 1.473(1.089-1.943) respectively of abdominal obesity among centenarians and the oldest-old respectively, and corresponding ORs 1.182(1.081-1.316) and 1.162(1.009-1.699) respectively of abdominal obesity among centenarians and the oldest-old respectively CONCLUSIONS AND IMPLICATIONS: In summary, the results based on CHCCS with the largest sample among centenarians and CHOCS showed that the blood glucose level and the prevalence of diabetes were at a lower level than those of adults or younger elderly. The results provide new evidence for target level of blood glucose control in those older elderly.
Authors: L Guariguata; D R Whiting; I Hambleton; J Beagley; U Linnenkamp; J E Shaw Journal: Diabetes Res Clin Pract Date: 2013-12-01 Impact factor: 5.602
Authors: Morten B Krag; Lars C Gormsen; Zengkui Guo; Jens S Christiansen; Michael D Jensen; Søren Nielsen; Jens O L Jørgensen Journal: Am J Physiol Endocrinol Metab Date: 2006-11-28 Impact factor: 4.310