Literature DB >> 32640160

Cine-Substitutions at Five-Membered Hetarenes Enabled by Sulfonium Salts.

Florian Berger1, Eva Maria Alvarez1, Nils Frank1, Kostiantyn Bohdan1, Mykhailo Kondratiuk1, Luca Torkowski1, Pascal S Engl1, Joana Barletta1, Tobias Ritter1.   

Abstract

We report a nucleophilic substitution reaction of five-membered hetarylsulfonium salts that results in a change of the substitution pattern on the arene. The products of these cine-substitutions are hard to access synthetically otherwise. The sulfonium salts that serve as starting materials are generated by a highly site-selective C-H functionalization reaction.

Entities:  

Year:  2020        PMID: 32640160     DOI: 10.1021/acs.orglett.0c02067

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  1 in total

1.  Trifluoromethyl Thianthrenium Triflate: A Readily Available Trifluoromethylating Reagent with Formal CF3+, CF3, and CF3- Reactivity.

Authors:  Hao Jia; Andreas P Häring; Florian Berger; Li Zhang; Tobias Ritter
Journal:  J Am Chem Soc       Date:  2021-05-14       Impact factor: 15.419

  1 in total

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