| Literature DB >> 32639494 |
Chathura S Abeywickrama1, Kaveesha J Wijesinghe2, Caroline B Plescia3, Lloyd S Fisher4, Theodore Goodson4, Robert V Stahelin3, Yi Pang5,6.
Abstract
The two-photon absorption properties of a pyrene-pyridinium dye (1) were studied for potential application in two-photon spectroscopy. When probe 1 was used in cellular two-photon fluorescence microscopy imaging, it allowed the visualization of nuclei in live cells with a relatively low probe concentration (such as 1 μM). Spectroscopic evidence further revealed that probe 1 interacted with DNA as an intercalator. The proposed DNA intercalation properties of probe 1 were consistent with the experimental findings that suggested that the observed nucleus staining ability is dependent on the substituents on the pyridinium fragment of the probe.Entities:
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Year: 2020 PMID： 32639494 DOI： 10.1039/d0pp00107d
Source DB: PubMed Journal: Photochem Photobiol Sci ISSN： 1474-905X Impact factor: 3.982