| Literature DB >> 32638274 |
Alais M Dall Agnol1,2, Raquel A Leme1,2, Suelen A Suphoronski1, Thalita E S Oliveira3, Flávia Possatti1, Viviane Saporiti1, Selwyn A Headley3, Amauri Alcindo Alfieri4,5, Alice Fernandes Alfieri1,2.
Abstract
We investigated the porcine lymphotropic herpesvirus (PLHV) DNA presence in multiple organs of pigs. Biological samples (n = 136) included tissue fragments of the central nervous system, heart, kidney, liver, lungs, spleen, urinary bladder, and urine. Sixty-eight (50%) organs were PLHV DNA-positive. None of the urine samples were detected with the virus genome. Although the presence of the PLHV DNA in the urinary bladder and kidney has been detected, it was not possible to show whether urine can be considered an effective route of virus shedding. This study warns to the risk of PLHV zoonotic transmission by xenotransplantation of tissues of porcine origin.Entities:
Keywords: PLHV; Pan-herpesvirus; Suid gammaherpesvirus; Swine
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Year: 2020 PMID： 32638274 PMCID： PMC7688735 DOI： 10.1007/s42770-020-00335-9
Source DB: PubMed Journal: Braz J Microbiol ISSN： 1517-8382 Impact factor: 2.476