Literature DB >> 326362

Eburicol, lichesterol, ergosterol, and obtusifoliol from polyene antibiotic-resistant mutants of Candida albicans.

R E Subden, L Safe, D C Morris, R G Brown, S Safe.   

Abstract

Two classes of polyene-resistant mutants were isolated from survivors of N-methyl-N'-nitro-N-nitrosoguanidine treatment of a wild-type Candida albicans. An analysis of the major sterols of one class revealed an accumulation of lichesterol and fecosterol while the other class accumulated eburicol, obtusifoliol, and lanosterol with minor quantities of C28 sterols.

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Year:  1977        PMID： 326362     DOI： 10.1139/m77-111

Source DB:  PubMed          Journal:  Can J Microbiol        ISSN： 0008-4166            Impact factor:   2.419


  4 in total

Review 1.  Amphotericin B: current understanding of mechanisms of action.

Authors:  J Brajtburg; W G Powderly; G S Kobayashi; G Medoff
Journal:  Antimicrob Agents Chemother       Date:  1990-02       Impact factor: 5.191

2.  Sterol and fatty acid composition of Candida lusitaniae clinical isolates.

Authors:  F Peyron; A Favel; R Calaf; A Michel-Nguyen; R Bonaly; J Coulon
Journal:  Antimicrob Agents Chemother       Date:  2002-02       Impact factor: 5.191

3.  Disruption of ergosterol biosynthesis, growth, and the morphological transition in Candida albicans by sterol methyltransferase inhibitors containing sulfur at C-25 in the sterol side chain.

Authors:  Ragu Kanagasabai; Wenxu Zhou; Jialin Liu; Thi Thuy Minh Nguyen; Phani Veeramachaneni; W David Nes
Journal:  Lipids       Date:  2004-08       Impact factor: 1.880

4.  Sterol composition in polyene antibiotic-sensitive and resistant strains of Malassezia pachydermatis.

Authors:  Y Uchida; S Onodera; T Nakade; K Otomo
Journal:  Vet Res Commun       Date:  1994       Impact factor: 2.459
  4 in total

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