Literature DB >> 3263602

Pharmacologic modulation of acute ocular inflammation. I. Adenosine.

G E Marak1, Y de Kozak, J P Faure, N A Rao, J L Romero, P A Ward, G O Till.   

Abstract

Modulation of signal transduction at the surface of inflammatory cells appears to influence acute inflammation. Adenosine, a well-known chemical messenger, inhibits the production of superoxide by stimulated neutrophils. In experimental allergic uveitis induced by sensitization with retinal 's' antigen, treatment with adenosine produced a marked reduction in the expected inflammation.

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Year:  1988        PMID： 3263602     DOI： 10.1159/000266646

Source DB:  PubMed          Journal:  Ophthalmic Res        ISSN： 0030-3747            Impact factor:   2.892


  6 in total

Review 1.  Receptor-mediated interaction between the sympathetic nervous system and immune system in inflammation.

Authors:  G Haskó
Journal:  Neurochem Res       Date:  2001-09       Impact factor: 3.996

2.  New bioinformatics approach to analyze gene expressions and signaling pathways reveals unique purine gene dysregulation profiles that distinguish between CD and UC.

Authors:  Leszek Rybaczyk; Andrew Rozmiarek; Kristin Circle; Iveta Grants; Bradley Needleman; Jacqueline E Wunderlich; Kun Huang; Fievos L Christofi
Journal:  Inflamm Bowel Dis       Date:  2009-07       Impact factor: 5.325

3.  Impact of disrupting adenosine A₃ receptors (A₃⁻/⁻ AR) on colonic motility or progression of colitis in the mouse.

Authors:  Tianhua Ren; Iveta Grants; Mazin Alhaj; Matt McKiernan; Marlene Jacobson; Hamdy H Hassanain; Wendy Frankel; Jacqueline Wunderlich; Fievos L Christofi
Journal:  Inflamm Bowel Dis       Date:  2010-12-03       Impact factor: 5.325

4.  Inosine protects against the development of diabetes in multiple-low-dose streptozotocin and nonobese diabetic mouse models of type 1 diabetes.

Authors:  Jon G Mabley; Alex Rabinovitch; Wilma Suarez-Pinzon; György Haskó; Pál Pacher; Robert Power; Gary Southan; Andrew Salzman; Csaba Szabó
Journal:  Mol Med       Date:  2003 Mar-Apr       Impact factor: 6.354

5.  Synergistic up-regulation of vascular endothelial growth factor expression in murine macrophages by adenosine A(2A) receptor agonists and endotoxin.

Authors:  Samuel Joseph Leibovich; Jiang-Fan Chen; Grace Pinhal-Enfield; Paula C Belem; Genie Elson; Anthony Rosania; Madhuri Ramanathan; Carmen Montesinos; Marlene Jacobson; Michael A Schwarzschild; J Stephen Fink; Bruce Cronstein
Journal:  Am J Pathol       Date:  2002-06       Impact factor: 4.307

6.  The adenosine A2A receptor agonist CGS 21680 fails to ameliorate the course of dextran sulphate-induced colitis in mice.

Authors:  Z Selmeczy; B Csóka; P Pacher; E S Vizi; G Haskó
Journal:  Inflamm Res       Date:  2007-05       Impact factor: 4.575
  6 in total

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