Vera Trocado1,2,3, Joana Silvestre-Machado1, Lídia Azevedo1, Alexandra Miranda1,2,4, Cristina Nogueira-Silva1,2,4. 1. Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal. 2. ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal. 3. Department of Obstetrics and Gynecology, Unidade Local de Saúde do Alto Minho, Viana do Castelo, Portugal. 4. Department of Obstetrics and Gynecology, Hospital de Braga, Braga, Portugal.
Abstract
BACKGROUND: There is limited information related to COVID-19 in pregnancy. OBJECTIVES: Evaluate the impact of COVID-19 during pregnancy.Search strategy: Searches were systematically carried out in PubMed, Scopus database and WHO database.Selection criteria: Studies with information related to the effects of COVID-19 in pregnancy, concerning maternal, obstetric, and neonatal outcomes were included.Data collection and analysis: Data were extracted for systematic review following PRISMA guidelines. CARE and STROBE were used to evaluate the quality of data.Main Results: A total of 8 studies involving 95 pregnant women and 51 neonates were included. Overall, the quality was considered good in four studies, moderate in three and poor in one. Among pregnant women, 26% had a history of epidemiological exposure to SARS-CoV-2. The most common symptoms presented were fever (55%), cough (38%) and fatigue (11%). In 50 deliveries, 94% were cesarean sections and 35% were preterm births. Of the 51 neonates, 20% had low birth weight and 1 tested positive for Sars-CoV-2. There was 1 neonatal death, not related to the viral infection, and no cases of severe neonatal asphyxia. CONCLUSIONS: The information compiled in this systematic review may help healthcare providers administer the best possible care.
BACKGROUND: There is limited information related to COVID-19 in pregnancy. OBJECTIVES: Evaluate the impact of COVID-19 during pregnancy.Search strategy: Searches were systematically carried out in PubMed, Scopus database and WHO database.Selection criteria: Studies with information related to the effects of COVID-19 in pregnancy, concerning maternal, obstetric, and neonatal outcomes were included.Data collection and analysis: Data were extracted for systematic review following PRISMA guidelines. CARE and STROBE were used to evaluate the quality of data.Main Results: A total of 8 studies involving 95 pregnant women and 51 neonates were included. Overall, the quality was considered good in four studies, moderate in three and poor in one. Among pregnant women, 26% had a history of epidemiological exposure to SARS-CoV-2. The most common symptoms presented were fever (55%), cough (38%) and fatigue (11%). In 50 deliveries, 94% were cesarean sections and 35% were preterm births. Of the 51 neonates, 20% had low birth weight and 1 tested positive for Sars-CoV-2. There was 1 neonatal death, not related to the viral infection, and no cases of severe neonatal asphyxia. CONCLUSIONS: The information compiled in this systematic review may help healthcare providers administer the best possible care.
Authors: Michael Ceulemans; Jan Y Verbakel; Kristel Van Calsteren; An Eerdekens; Karel Allegaert; Veerle Foulon Journal: Int J Environ Res Public Health Date: 2020-09-17 Impact factor: 3.390