Asghar Zarei1, Babak Mohammadzadeh Asl2. 1. Department of Biomedical Engineering, Tarbiat Modares University, Tehran, Iran. 2. Department of Biomedical Engineering, Tarbiat Modares University, Tehran, Iran. Electronic address: babakmasl@modares.ac.ir.
Abstract
BACKGROUND AND OBJECTIVE: This paper addresses the automated recognition of obstructive sleep apnea (OSA) from the analysis of single-lead ECG signals. This is one of the most important problems that is, critical to the realization of monitoring patients with sleep apnea. METHODS: In the present study, a novel solution based on autoregressive (AR) modeling of the single-lead ECG, and spectral autocorrelation function as an ECG feature extraction method is presented. The more effective features are opted by sequential forward feature selection (SFFS) technique and fed into the random forest for binary classification between the apnea and normal events. RESULTS: Experimental results on Apnea-ECG database proved that the introduced algorithm resulted in an accuracy of 93.90% (sensitivity of 92.26% and specificity of 94.92%) in per-segment classification, which outperforms the other cutting-edge automatic OSA recognition techniques. Moreover, the proposed algorithm provided an accuracy of 97.14% (sensitivity of 95.65% and specificity of 100%) in discrimination of apnea patients from the normal subjects, which is comparable to the traditional and existing approaches. CONCLUSIONS: This study suggests that automatic OSA recognition from single-lead ECG signals is possible, which can be used as an inexpensive and low complexity burden alternative to more conventional methods such as Polysomnography.
BACKGROUND AND OBJECTIVE: This paper addresses the automated recognition of obstructive sleep apnea (OSA) from the analysis of single-lead ECG signals. This is one of the most important problems that is, critical to the realization of monitoring patients with sleep apnea. METHODS: In the present study, a novel solution based on autoregressive (AR) modeling of the single-lead ECG, and spectral autocorrelation function as an ECG feature extraction method is presented. The more effective features are opted by sequential forward feature selection (SFFS) technique and fed into the random forest for binary classification between the apnea and normal events. RESULTS: Experimental results on Apnea-ECG database proved that the introduced algorithm resulted in an accuracy of 93.90% (sensitivity of 92.26% and specificity of 94.92%) in per-segment classification, which outperforms the other cutting-edge automatic OSA recognition techniques. Moreover, the proposed algorithm provided an accuracy of 97.14% (sensitivity of 95.65% and specificity of 100%) in discrimination of apneapatients from the normal subjects, which is comparable to the traditional and existing approaches. CONCLUSIONS: This study suggests that automatic OSA recognition from single-lead ECG signals is possible, which can be used as an inexpensive and low complexity burden alternative to more conventional methods such as Polysomnography.