Literature DB >> 326332

Treatmenf of optic neuritis by retrobulbar injection of triamcinolone.

E S Gould, A C Bird, P K Leaver, W I McDonald.   

Abstract

In a single-blind controlled clinical trial patients with optic neuritis caused by demyelination were given a single retrobulbar injection of triamcinolone. Though the treated group showed a trend towards more rapid recovery of vision than the controls, there was no significant difference in visual acuity, colour vision, or visual fields during the first six months after treatment. We conclude that routine use of corticosteroids is not justified in unilateral optic neuritis when vision in the other eye is good. Shortening the period of visual disability in bilateral disease or unilateral disease when vision in the other eye is poor, however, may be justifiable.

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Year:  1977        PMID: 326332      PMCID: PMC1607274          DOI: 10.1136/bmj.1.6075.1495

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  6 in total

1.  Treatment of acute retrobulbar neuritis with corticotrophin.

Authors:  M D Rawson; L A Liversedge; G Goldfarb
Journal:  Lancet       Date:  1966-11-12       Impact factor: 79.321

2.  Prognosis in optic neuritis related to age.

Authors:  C J Earl; B Martin
Journal:  Lancet       Date:  1967-01-14       Impact factor: 79.321

3.  Practolol in the treatment of cardiac dysrhythmias due to acute myocardial infarction.

Authors:  D E Jewitt; C J Mercer; J P Shillingford
Journal:  Lancet       Date:  1969-08-02       Impact factor: 79.321

4.  Orbital infusion of steroids in the rabbit.

Authors:  N D Levine; S B Aronson
Journal:  Arch Ophthalmol       Date:  1970-05

5.  Ischaemic optic neuropathy. The clinical profile and history.

Authors:  D R Boghen; J S Glaser
Journal:  Brain       Date:  1975-12       Impact factor: 13.501

6.  A trial of corticotrophin gelatin injection in acute optic neuritis.

Authors:  A N Bowden; P M Bowden; A I Friedmann; G D Perkin; F C Rose
Journal:  J Neurol Neurosurg Psychiatry       Date:  1974-08       Impact factor: 10.154

  6 in total
  12 in total

Review 1.  Physicians, subsequence and consequence.

Authors:  W I McDonald
Journal:  J Neurol Neurosurg Psychiatry       Date:  1999-09       Impact factor: 10.154

2.  Acute Optic Neuritis.

Authors: 
Journal:  Curr Treat Options Neurol       Date:  1999-03       Impact factor: 3.598

Review 3.  The ocular manifestations of multiple sclerosis. 1. Abnormalities of the afferent visual system.

Authors:  W I McDonald; D Barnes
Journal:  J Neurol Neurosurg Psychiatry       Date:  1992-09       Impact factor: 10.154

Review 4.  Corticosteroids for treating optic neuritis.

Authors:  Robin L Gal; Satyanarayana S Vedula; Roy Beck
Journal:  Cochrane Database Syst Rev       Date:  2015-08-14

Review 5.  Corticosteroids for treating optic neuritis.

Authors:  S S Vedula; S Brodney-Folse; R L Gal; R Beck
Journal:  Cochrane Database Syst Rev       Date:  2007-01-24

Review 6.  Role of steroids and immunosuppression and effects of interferon beta-1b in multiple sclerosis.

Authors:  D E Goodkin
Journal:  West J Med       Date:  1994-09

7.  Optic neuropathy in sarcoidosis.

Authors:  E M Graham; C J Ellis; M D Sanders; W I McDonald
Journal:  J Neurol Neurosurg Psychiatry       Date:  1986-07       Impact factor: 10.154

8.  [Steroids for optic nerve diseases?].

Authors:  W A Lagrèze
Journal:  Ophthalmologe       Date:  2007-06       Impact factor: 1.059

9.  Suprathreshold vision in acute optic neuritis.

Authors:  J Sjöstrand; M Abrahamsson
Journal:  J Neurol Neurosurg Psychiatry       Date:  1982-03       Impact factor: 10.154

10.  Visual evoked potentials after optic neuritis. Effect of time interval, age and disease dissemination.

Authors:  S J Jones
Journal:  J Neurol       Date:  1993-09       Impact factor: 4.849

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