Literature DB >> 32627182

Induction of diverse T cell memory through antibody-mediated activation in mice.

Matthew D Taylor1, Mariana R Brewer1, Clifford S Deutschman1.   

Abstract

Recent studies have demonstrated that laboratory mice lack a robust repertoire of memory T cell. Administration of an anti-CD3ε activating antibody (clone 145-2C11) induces persistent CD4 and CD8 T cell memory in both lymphatic and solid organs while maintaining T cell responses and without increased anergy or altering innate immunity.
© 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  CD 8 T cells; CD4 T cells; T cell activation; T cell memory formation; anti-CD3ε antibody

Mesh：

Substances：

Year:  2020        PMID： 32627182      PMCID： PMC8019190          DOI： 10.1002/eji.202048570

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN： 0014-2980            Impact factor:   5.532


  7 in total

1.  Anti-CD3 priming generates heterogeneous antigen-specific memory CD4 T cells.

Authors:  Deepa S Patke; Mojgan Ahmadzadeh; Adam W Bingaman; Donna L Farber
Journal:  Clin Immunol       Date:  2005-09-06       Impact factor: 3.969

2.  CD8 T Cell Memory Increases Immunopathology in the Perforin-Deficient Model of Hemophagocytic Lymphohistiocytosis Secondary to TNF-α.

Authors:  Matthew D Taylor; Thomas N Burn; E John Wherry; Edward M Behrens
Journal:  Immunohorizons       Date:  2018-02

3.  Inter-mouse strain differences in the in vivo anti-CD3 induced cytokine release.

Authors:  C Ferran; M Dy; K Sheehan; S Merite; R Schreiber; P Landais; G Grau; J Bluestone; J F Bach; L Chatenoud
Journal:  Clin Exp Immunol       Date:  1991-12       Impact factor: 4.330

4.  In vivo administration of anti-murine CD3 monoclonal antibody induces selective, long-term anergy in CD8+ T cells.

Authors:  E S Woodle; S Hussein; J A Bluestone
Journal:  Transplantation       Date:  1996-03-15       Impact factor: 4.939

5.  The comparative immunology of wild and laboratory mice, Mus musculus domesticus.

Authors:  Stephen Abolins; Elizabeth C King; Luke Lazarou; Laura Weldon; Louise Hughes; Paul Drescher; John G Raynes; Julius C R Hafalla; Mark E Viney; Eleanor M Riley
Journal:  Nat Commun       Date:  2017-05-03       Impact factor: 14.919

6.  Detuning CD8 T cells: down-regulation of CD8 expression, tetramer binding, and response during CTL activation.

Authors:  Zhengguo Xiao; Matthew F Mescher; Stephen C Jameson
Journal:  J Exp Med       Date:  2007-10-22       Impact factor: 14.307

7.  Normalizing the environment recapitulates adult human immune traits in laboratory mice.

Authors:  Lalit K Beura; Sara E Hamilton; Kevin Bi; Jason M Schenkel; Oludare A Odumade; Kerry A Casey; Emily A Thompson; Kathryn A Fraser; Pamela C Rosato; Ali Filali-Mouhim; Rafick P Sekaly; Marc K Jenkins; Vaiva Vezys; W Nicholas Haining; Stephen C Jameson; David Masopust
Journal:  Nature       Date:  2016-04-20       Impact factor: 49.962
  7 in total
  3 in total

1.  T cell activation and IFNγ modulate organ dysfunction in LPS-mediated inflammation.

Authors:  Matthew D Taylor; Tiago D Fernandes; Omar Yaipen; Cassidy E Higgins; Christine A Capone; Daniel E Leisman; Ana Nedeljkovic-Kurepa; Mabel N Abraham; Mariana R Brewer; Clifford S Deutschman
Journal:  J Leukoc Biol       Date:  2022-02-09       Impact factor: 6.011

2.  CD4 T Follicular Helper Cells Prevent Depletion of Follicular B Cells in Response to Cecal Ligation and Puncture.

Authors:  Matthew D Taylor; Mariana R Brewer; Ana Nedeljkovic-Kurepa; Yihe Yang; Kalpana S Reddy; Mabel N Abraham; Betsy J Barnes; Clifford S Deutschman
Journal:  Front Immunol       Date:  2020-08-12       Impact factor: 7.561

3.  CD4 and CD8 T Cell Memory Interactions Alter Innate Immunity and Organ Injury in the CLP Sepsis Model.

Authors:  Matthew D Taylor; Tiago D Fernandes; Alexander P Kelly; Mabel N Abraham; Clifford S Deutschman
Journal:  Front Immunol       Date:  2020-11-20       Impact factor: 7.561
  3 in total

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