Literature DB >> 3262584

Serum levels of RHP and of unbound C1q in rheumatoid arthritis and systemic lupus erythematosus.

C L Rosano1, N Parhami, K E Hechemy, C Hurwitz.   

Abstract

RHP is a recently described serum protein which inhibits a number of physiologic functions of C1q unbound to C1r2 x C1s2. In this report we show that sera from patients with rheumatoid arthritis contained elevated levels of RHP and of unbound C1q. Sera from patients with systemic lupus erythematosus contained normal levels of RHP and were characterized by deficits of C1q required to form C1 from existing levels of C1r and C1s.

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Year:  1988        PMID: 3262584     DOI: 10.1007/bf00915770

Source DB:  PubMed          Journal:  Inflammation        ISSN: 0360-3997            Impact factor:   4.092


  20 in total

1.  A rosette assay for the determination of C 1 q receptor-bearing cells.

Authors:  Y Gabay; H Perlmann; P Perlmann; A T Sobel
Journal:  Eur J Immunol       Date:  1979-10       Impact factor: 5.532

2.  Inhibition of C1q functions by RHP, a protein elevated in sera from patients with rheumatoid arthritis.

Authors:  C L Rosano; C B Braun; K E Hechemy; N Parhami; P S Satoh; C Hurwitz
Journal:  Complement       Date:  1988

3.  Isolation and purification of a Clq-anti Clq precipitin ring enhancing protein from sera of patients with rheumatoid arthritis.

Authors:  C L Rosano; N Parhami; C Hurwitz
Journal:  Biochem Biophys Res Commun       Date:  1985-05-16       Impact factor: 3.575

4.  The dissociation properties of native C1.

Authors:  R J Ziccardi; J Tschopp
Journal:  Biochem Biophys Res Commun       Date:  1982-07-30       Impact factor: 3.575

5.  Identification of types of cells in human peripheral blood that bind C1q.

Authors:  A J Tenner; N R Cooper
Journal:  J Immunol       Date:  1981-03       Impact factor: 5.422

6.  Fibronectin binds to the C1q component of complement.

Authors:  D H Bing; S Almeda; H Isliker; J Lahav; R O Hynes
Journal:  Proc Natl Acad Sci U S A       Date:  1982-07       Impact factor: 11.205

7.  Determination of C1q in human sera.

Authors:  C L Rosano; N Parhami; C Hurwitz
Journal:  J Lab Clin Med       Date:  1979-10

8.  Low molecular weight C1q in systemic lupus erythematosus.

Authors:  R Hoekzema; A J Hannema; T J Swaak; J Paardekooper; C E Hack
Journal:  J Immunol       Date:  1985-07       Impact factor: 5.422

9.  Enhanced binding and degradation of the C1q subcomponent of complement by thioglycollate-stimulated guinea pig peritoneal macrophages.

Authors:  R Veerhuis; N Klar-Mohamad; L A van Es; M R Daha
Journal:  Scand J Immunol       Date:  1986-05       Impact factor: 3.487

10.  The interaction of human plasma fibronectin with a subunit of the first component of complement, C1q.

Authors:  E Pearlstein; J Sorvillo; I Gigli
Journal:  J Immunol       Date:  1982-05       Impact factor: 5.422

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