| Literature DB >> 32623579 |
Leiyang Li1,2, Haixiao Liu1, Jianing Luo1, Zhijun Tan3, Junmei Gao1, Ping Wang1, Wenting Jing1, Ruixi Fan1, Xiaoyang Zhang1, Hao Guo1, Hao Bai1, Wenxing Cui1, Xun Wu1, Yan Qu4, Wei Guo5.
Abstract
Recently, minimally invasive techniques, including endoscopic evacuation and minimally invasive catheter (MIC) evacuation, have been used for the treatment of patients with spontaneous cerebellar hemorrhage (SCH). However, credible evidence is still needed to validate the effects of these techniques. To explore the long-term outcomes of both surgical techniques in the treatment of SCH. Fifty-two patients with SCH who received endoscopic evacuation or MIC evacuation were retrospectively reviewed. Six-month mortality and the modified Rankin Scale (mRS) score were the primary and secondary outcomes, respectively. A multivariate logistic regression model was used to assess the effects of the different surgical techniques on patient outcomes. In the present study, the mortality rate for the entire cohort was 34.6%. Univariate analysis showed that the surgical technique and preoperative Glasgow Coma Scale (GCS) score affected 6-month mortality. However, no variables were found to be correlated with 6-month mRS scores. Further multivariate analysis demonstrated that 6-month mortality in the endoscopic evacuation group was significantly lower than that in the MIC evacuation group (OR = 4.346, 95% CI 1.056 to 17.886). The 6-month mortality rate in the preoperative GCS 9-14 group was significantly lower than that in the GCS 3-8 group (OR = 7.328, 95% CI 1.723 to 31.170). Compared with MIC evacuation, endoscopic evacuation significantly decreased 6-month mortality in SCH patients. These preliminary results warrant further large, prospective, randomized studies.Entities:
Keywords: Minimally invasive catheter; Neuroendoscopy; Retrospective studies; Spontaneous cerebellar hemorrhage; Treatment outcome
Year: 2020 PMID: 32623579 PMCID: PMC7803713 DOI: 10.1007/s12975-020-00827-8
Source DB: PubMed Journal: Transl Stroke Res ISSN: 1868-4483 Impact factor: 6.829