Literature DB >> 32622830

Practical management of C3 glomerulopathy and Ig-mediated MPGN: facts and uncertainties.

Fadi Fakhouri1, Moglie Le Quintrec2, Véronique Frémeaux-Bacchi3.   

Abstract

In recent years, a substantial body of experimental and clinical work has been devoted to C3 glomerulopathy and Ig-mediated membranoproliferative glomerulonephritis. Despite the rapid accumulation of data, several uncertainties about these 2 rare forms of nephropathies persist. They concern their pathophysiology, classification, clinical course, relevance of biomarkers and of pathology findings, and assessment of the efficacy of the available therapies. The present review discusses the impact of these uncertainties on the clinical management of patients.
Copyright © 2020 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  C3 glomerulopathy; Ig-mediated membranoproliferative glomerulonephritis; complement

Mesh：

Substances：

Year:  2020        PMID： 32622830     DOI： 10.1016/j.kint.2020.05.053

Source DB:  PubMed          Journal:  Kidney Int        ISSN： 0085-2538            Impact factor:   10.612


  5 in total

1.  Prognostication for C3 Glomerulopathy and Idiopathic Immunoglobulin-Associated Membranoproliferative Glomerulonephritis.

Authors:  Fernando Caravaca-Fontán; Manuel Praga
Journal:  Clin J Am Soc Nephrol       Date:  2022-07       Impact factor: 10.614

Review 2.  The Rational Use of Complement Inhibitors in Kidney Diseases.

Authors:  Fadi Fakhouri; Nora Schwotzer; Déla Golshayan; Véronique Frémeaux-Bacchi
Journal:  Kidney Int Rep       Date:  2022-03-04

3.  A Young Patient with Microscopic Polyangiitis Requiring Hemodialysis with Complications of Repeated Episodes of Posterior Reversible Encephalopathy Syndrome Probably Due to Different Etiologies.

Authors:  Shinichiro Asakawa; Shigeyuki Arai; Mika Kawagoe; Chiaki Ohata; Wataru Ono; Hiroshi Murata; Yoshifuru Tamura; Shunya Uchida; Shigeru Shibata; Yoshihide Fujigaki
Journal:  Intern Med       Date:  2021-10-12       Impact factor: 1.282

Review 4.  Nephritis-Associated Plasmin Receptor (NAPlr): An Essential Inducer of C3-Dominant Glomerular Injury and a Potential Key Diagnostic Biomarker of Infection-Related Glomerulonephritis (IRGN).

Authors:  Nobuyuki Yoshizawa; Muneharu Yamada; Masayuki Fujino; Takashi Oda
Journal:  Int J Mol Sci       Date:  2022-09-01       Impact factor: 6.208

Review 5.  Complement Components in the Diagnosis and Treatment after Kidney Transplantation-Is There a Missing Link?

Authors:  Małgorzata Kielar; Agnieszka Gala-Błądzińska; Paulina Dumnicka; Piotr Ceranowicz; Maria Kapusta; Beata Naumnik; Grzegorz Kubiak; Marek Kuźniewski; Beata Kuśnierz-Cabala
Journal:  Biomolecules       Date:  2021-05-21
  5 in total

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