Literature DB >> 32621

Fertilization: a uterine glycosaminoglycan stimulates the conversion of sperm proacrosin to acrosin.

T J Wincek, R F Parrish, K L Polakoski.   

Abstract

Acrosin is a proteinase required for mammalian fertilization, and in freshly ejaculated spermatozoa exists as an inactive zymogen, proacrosin. A factor prsent in uterine flushings of gilts stimulates the conversion of highly pruified boar proacrosin to acrosin. Characterization of this factor indicates that its active component is a glycosaminoglycan.

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Year:  1979        PMID: 32621     DOI: 10.1126/science.32621

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  2 in total

1.  Inhibition by heparin-modulated antithrombin III of amidolysis catalysed by m beta-acrosin.

Authors:  W F Long; F B Williamson
Journal:  Biochem J       Date:  1984-02-01       Impact factor: 3.857

2.  Quantitative changes of Ricinus communis agglutinin I and Helix pomatia lectin binding sites in the acrosome of rat spermatozoa during epididymal transit.

Authors:  L Hermo; R Winikoff; F W Kan
Journal:  Histochemistry       Date:  1992-09
  2 in total

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